Preparations of 1-hydroxyindole derivatives and their potent inhibitory activities on platelet aggregation

Article abstract of DOI:10.3987/COM-96-7537

1-Hydroxymelatonin, 5-bromo- and 5,7-dibromo-1-hydroxytryptamine derivatives, 1,4-dihydroxy-5-nitroindole, 1-hydroxy-3-methylsulfinylmethylindole, and 5-acetyl-1,3,4,5-tetrahydro-1-hydroxypyrrolo[4,3,2-de]quinoline were synthesized for the first time. 1-Hydroxyindoles revealed potent inhibitory activities on platelet aggregation.