First Total Synthesis of Mycinamicin IV and VII. Succesful Application of New Glycosidation Reaction

Article abstract of DOI:10.1016/0040-4039(88)85296-1

First total synthesis of mycinamicin IV via mycinamicin VII is described.New glycosidation reaction using Cp2MCl2-AgClO4 (M=Zr, Hf) was effectively applied to the selective introduction of β-D-mycinosyl and β-D-desosaminyl linkages.