On the Michael Type Addition of Dipeptides to 4-Oxo-4-phenyl-2-butenoic Acid Derivatives

Article abstract of DOI:10.1007/BF00809215

The title reaction afforded the adducts 3 in variable selectivity, but the isomers of (S,S,S)-configuration were easily isolated; the reversibility of the reaction permits the recovery of the starting materials from the mother liquor.High selectivity has been observed in one case only. - Keywords: Michael type addition; 4-Oxo-4-phenyl-2-butenoic acids; (S)-Alanyl-(S)-proline; (S)-Lysyl-(S)-proline