
Journal of Organic Chemistry p. 5136 - 5138 (1994)
Update date:2022-08-11
Topics:
Denmark, Scott E.
Griedel, Brian D.
Asymmetrically modified S,O-(alkoxysilacyclobutyl)ketene acetals derived from methane thiol esters reacted with aromatic aldehydes at low temperature to afford, after desilylation, the corresponding β-hydroxythiol ester aldolates in high enantiomeric excess (91-94percent ee).
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