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A one-pot synthesis of 4-methylpyrano[3,2-c]quinolin-2,5[6H]-diones

DOI: 10.1515/HC.2004.10.4-5.289

Source and publish data:

Heterocyclic Communications p. 289 - 294 (2004)

Update date:2022-08-29

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Authors:

Venkatesh KumarVenkatesh Kumar

RajendranRajendran

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Article abstract of DOI:10.1515/HC.2004.10.4-5.289

4-hydroxy-2-quinolone being endowed with both nucleophilic and electrophilic properties furnishes the dimeric quinoline in a base catalyzed self-condensation process. A one step synthesis, starting from 4-hydroxy-2-quinolone with ethyl acetoacetate and pyridine proceeded through the Michael addition, which was followed by cyclization, gave an angular isomer 4-methylpyrano[3,2-c]quinolin-2,5[6H]-dione. The reaction was then extended to synthesize further derivatives of angular pyrano quinolones. Structures of all the products have been established by spectral and elemental analysis data.

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Full text of DOI:10.1515/HC.2004.10.4-5.289

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Authenticated  
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Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/21/15 8:44 PM  
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Product name:4-methyl-2H-pyrano[3,2-c]quinoline-2,5(6H)-dione

Cas No:79359-44-7

79359-44-7

R&D Labs maybe for 79359-44-7

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