Nickel Catalyzed Imine Aldol Reactions between Activated Imines and Pronucleophiles

DOI: 10.1016/00404-0399(50)0912V-

Source and publish data:

Tetrahedron Letters p. 5023 - 5026 (1995)

Update date:2022-08-11

Topics:

Authors:

Shida, Naomi

Kubota, Yasufumi

Fukui, Hiroyuki

Asao, Naoki

Kadota, Isao

Yamamoto, Yoshinori

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Article abstract of DOI:10.1016/00404-0399(50)0912V-

Treatment of activated imines 1 with carbonyl compounds 2 in the presence of catalytic amounts of NiCl2(PPh3)2 or NiBr2(PPh3)2 at room temperature affords imine aldol products 3 in high to good yields.

Full text of DOI:10.1016/00404-0399(50)0912V-

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