THE DEPENDENCE OF ASYMMETRIC INDUCTION ON SOLVENT POLARITY AND TEMPERATURE IN PEPTIDE SYNTHESIS

DOI: 10.1016/S0040-4039(01)81905-5

Source and publish data:

Tetrahedron Letters p. 3361 - 3364 (1981)

Update date:2022-08-16

Topics:

Authors:

Benoiton, N. Leo

Kuroda, K.

Chen, F. M. F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)81905-5

When a racemic 2,4-dialkyl-5(4H)-oxazolone reacts with an L-amino acid ester, the D-L epimer is formed in excess in apolar solvents and the L-L epimer is formed in excess in polar solvents, the proportion of L-L isomer increasing with decreasing temperature.

Full text of DOI:10.1016/S0040-4039(01)81905-5

Products guided by the article

Product name:(S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester

Cas No:80680-98-4

R&D Labs maybe for 80680-98-4

Suzhou Chiral Pharmaceuticals Co., Ltd.

Contact:86-0512-63197058

Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Reliable Pharma Technology (Shanghai) Co., Ltd.

Contact:0086-21-67676847-8008

Address:Lane 1500, No.68, Xinfei Road, Songjiang District, Shanghai, 201611, P.R.China.
Fujian Wanke Pharmaceutical Co., LTD.

Contact:+86-598-5026002

Address:Economic development zone,jiangle county
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City

Relevant to this article

Reactions of 2,4-disubstituted 5-nitro-1,2,3-triazole 1-oxides. 2. Oxidation of 2-substituted 4-amino(alkylamino)-5-nitro-1,2,3-triazole 1-oxides

Doi:10.1007/BF02323375
(1999)
Foldamer-templated catalysis of macrocycle formation

Doi:10.1126/science.aax7344
(2019)
Novel and highly efficient synthesis of substituted dibenz[b,g]1,5- oxazocines. A direct comparison of the solution versus solid-phase approach

Doi:10.1016/S0040-4020(00)00120-4
(2000)
Preparation of chiral α-monofluoroalkylphosphonic acids and their evaluation as inhibitors of protein tyrosine phosphatase 1B

Doi:10.1039/a908086d
(2000)
Molecular basis of the interaction of novel tributyltin(IV) 2/4-[(E)-2-(aryl)-1-diazenyl]benzoates endowed with an improved cytotoxic profile: Synthesis, structure, biological efficacy and QSAR studies

Doi:10.1016/j.jinorgbio.2010.05.001
(2010)
Stoichiometric and Catalytic C?C and C?H Bond Formation with B(C₆F₅)₃ via Cationic Intermediates

Doi:10.1002/anie.201704789
(2017)

Article Doi