Journal of the American Chemical Society p. 7588 - 7591 (1984)
Update date:2022-08-10
Topics:
Johnson, William S.
Edington, Clare
Elliott, John D.
Silverman, I. Robert
A procedure has been developed for the coupling of acetals 4-7 derived from (R,R)-2,4-pentanediol with α-silyl ketones or enol silyl ethers to give aldol ethers 8/9 in excellent yield and high diastereoselectivity, 8:9 = >95:5.This methodology has been ap
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