Use of 2,5-Dichlorophenyl Phosphorodichloridothioate in the Synthesis of Diastereoisomeric Dinucleoside Phosphorothioates

DOI: 10.1039/c39830000591

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 591 - 593 (1983)

Update date:2022-08-30

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Authors:

Kemal, Oeznur

Reese, Colin B.

Serafinowska, T.

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Article abstract of DOI:10.1039/c39830000591

A convenient method for the synthesis, by the phosphotriester approach, of dinucleoside phosphorothioates is illustrated by the preparation and isolation of the pure Rp- and Sp-diastereoisomers of thymidine-3'-thymidine-5' phosphorothioate (5)

Full text of DOI:10.1039/c39830000591

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