Thermal Cycloaddition of Dimethyl 1,2,4,5-Tetrazine-3,6-dicarboxylate with Electron-Rich Olefins: 1,2-Diazine and Pyrrole Introduction. Preparation of Octamethylporphin (OMP)

Article abstract of DOI:10.1021/jo00197a015

An investigation of the inverse electron demand Diels-Alder reactions of dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate with electron-rich olefins for the introduction of 1,2-diazines and pyrroles is described.A short synthesis of 2,3,7,8,12,13,17,18-octamethylporphin (OMP) is detailed.