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Synthesis of alpha-deuterium-labelled cyclohexylamine and its deamination by rabbit liver microsomes.

DOI: 10.1248/cpb.37.1097

Source and publish data:

Chemical and pharmaceutical bulletin p. 1097 - 1099 (1989)

Update date:2022-08-11

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Authors:

KurebayashiKurebayashi

FukuokaFukuoka

TanakaTanaka

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Article abstract of DOI:10.1248/cpb.37.1097

In order to investigate the isotope effect on the microsomal oxidative deamination of cyclohexylamine, alpha-deuterium(D)-labelled cyclohexylamine was synthesized. The deuterium labelling was found exclusively at the alpha-position with a purity of greate

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Full text of DOI:10.1248/cpb.37.1097

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