A USEFUL METHOD FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS: A SHORT ENANTIOSPECIFIC SYNTHESIS OF (R)- AND (S)-SULCATOL

Article abstract of DOI:10.1016/S0040-4039(00)99105-6

The epimeric 2-(1-Hydroxyethyl)-5-methyl-4-hexanoic acids have been prepared by bakers yeast reduction of the corresponding oxo compound or by alkylation of an optically pure 3-hydroxybutanoate.Radical chain decarboxylation afforded the antipodes of sulca