Solid phase applications of Dde and the analogue Nde: Synthesis of trypanothione disulphide

Article abstract of DOI:10.1016/S0040-4039(97)01010-1

Bis - Dde and Nde spermidine derivatives selectively protected on the primary amines were readily prepared and attached via the secondary amine group to a p-nitrophenyl-1-chloroformate pre-activated HMPA resin. Deprotection for Nde was monitored by colour