Journal of Medicinal Chemistry p. 3452 - 3458 (1994)
Update date:2022-08-10
Topics:
Mauger
Burke
Somani
Friedlos
Knox
The synthesis and properties of some prodrug candidates for antibody- directed enzyme prodrug therapy (ADEPT) are described. These compounds have been designed to generate the corresponding active drug upon interaction with a bacterial nitroreductase that
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