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Chemistry informtion about N-Trimethylsilylacetamide (CAS NO.13435-12-6) is:
IUPAC Name: N-Trimethylsilylacetamide
Synonyms: (Acetylamino)Trimethylsilane ; N-(Trimethylsilyl)-Acetamid ; N-Trimethylsilylacetamide ; Trimethylsilylacetamide ; Tmsa ; Tms Acetamide ; N-Trimethylsilylacetamidea.R. ; Acetamide, N-(Trimethylsilyl)-
MF: C5H13NOSi
MW: 131.25
EINECS: 236-565-7
Density: 0.859 g/cm3
Melting Point: 46-49 °C(lit.)
Flash Point: 44.1 °C
Boiling Point: 190.2 °C at 760 mmHg
Vapour Pressure: 0.548 mmHg at 25°C
Enthalpy of Vaporization: 42.64 kJ/mol
Storage temp.: Flammables area
Sensitive Moisture: Sensitive
BRN: 741928
Product Categories: Analytical Chemistry ; GC Derivatizing Reagents ; Si (Classes of Silicon Compounds) ; Silicon Compounds (for Synthesis) ; Silylacetamides ; Silylation (GC Derivatizing Reagents) ; Si-N Compounds ; Synthetic Organic Chemistry ; Trimethylsilylation (GC Derivatizing Reagents)
Following is the molecular structure of N-Trimethylsilylacetamide (CAS NO.13435-12-6) is:
Its preparation products is cefdinir .
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LDLo | intraperitoneal | 350mg/kg (350mg/kg) | immunological including allergic: decreased immune response | Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975Vol. 27MAY1975, |
Reported in EPA TSCA Inventory.
Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
Xi
F
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
R11:Highly flammable.
Safety Statements:
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: 1325
WGK Germany:3
RTECS: AD0250000
F:
F 10: Keep under argon.
F 21: Sensitive to humidity.
TSCA: Yes
HazardClass: 4.1
PackingGroup: III
N-Trimethylsilylacetamide (CAS NO.13435-12-6) is a white to yellowish crystalline mass.
First Aid Measures:
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.
Handling and Storage:
Handling: Use spark-proof tools and explosion proof equipment. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.