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Nitroguanidine

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Name

Nitroguanidine

EINECS 209-143-5
CAS No. 556-88-7 Density 2.009 g/cm3
PSA 107.72000 LogP 0.37530
Solubility 3 g/L (20 ºC) Melting Point 239 °C (dec.)(lit.)
Formula CH4N4O2 Boiling Point 219.348 °C at 760 mmHg
Molecular Weight 104.068 Flash Point 86.459 °C
Transport Information UN 1336 4.1/PG 1 Appearance white needle crystal
Safety 16-26-33-36/37/39-47-37/39 Risk Codes 11-36/37/38-5
Molecular Structure Molecular Structure of 556-88-7 (Nitroguanidine) Hazard Symbols FlammableF,IrritantXi
Synonyms

Guanidine,nitro- (8CI,9CI);2-Nitroguanidine;N1-Nitroguanidine;NQ;NSC 41036;Nitroguanidine;N''-Nitroguanidine;Picrite;Picrite (propellant);a-Nitroguanidine;b-Nitroguanidine;

Article Data 34

Nitroguanidine Synthetic route

506-93-4

guanidine nitrate

556-88-7

nitroguanidine

Conditions
ConditionsYield
With sulfuric acid at 20℃;100%
With 15-crown-5; nitric acid at 5 - 32℃; for 0.666667h; Reagent/catalyst; Temperature;99.4%
With sulfuric acid
62154-79-4

nitro-azidocarboxamidine

556-88-7

nitroguanidine

Conditions
ConditionsYield
With sodium dithionite
674-81-7

nitrosoguanidine

556-88-7

nitroguanidine

Conditions
ConditionsYield
With potassium permanganate; nitric acid
593-84-0

guanidinium thiocyanate

556-88-7

nitroguanidine

Conditions
ConditionsYield
With sulfuric acid; nitric acid
With sulfuric acid; nitric acid
594-14-9

guanidinium sulfate

556-88-7

nitroguanidine

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 20℃;
With sulfuric acid; nitric acid β-Form; nachfolgenden Erwaermen auf dem Wasserbad und Eingiessen in Eiswasser;
With nitric acid
7697-37-2

nitric acid

113-00-8

guanidine nitrate

556-88-7

nitroguanidine

Conditions
ConditionsYield
reagiert das Guanidinsalz;
18264-75-0

3-amino-1-nitroguanidine

aqueous (NH4)2CO3

aqueous (NH4)2CO3

A

556-88-7

nitroguanidine

B

79-17-4

aminoguanidine

C

302-01-2

hydrazine

D

diaminoguanidine

diaminoguanidine

Conditions
ConditionsYield
Produkt 5: Guanidin;
α-form of nitroguanidine

α-form of nitroguanidine

556-88-7

nitroguanidine

Conditions
ConditionsYield
β-Form; neben anderen Produkten;
β-nitroguanidine

β-nitroguanidine

556-88-7

nitroguanidine

Conditions
ConditionsYield
With sulfuric acid; water α-Form;
benzenesulfonate guanylurea

benzenesulfonate guanylurea

556-88-7

nitroguanidine

Conditions
ConditionsYield
With nitric acid

Nitroguanidine Chemical Properties

Product Name: Nitroguanidine (CAS NO.556-88-7):


IUPAC NAME: 2-Nitroguanidine
Molecular Formula: CH4N4O2
Molecular Weight: 104.07 g/mol
CAS No.: 556-88-7
EINECS: 209-143-5
RTECS: MF4600000
RTECS Class: Drug ;  Mutagen ;  Primary Irritant
Melting Point: 239 °C (dec.)(lit.)
Density: 2 g/cm3 
Flash Point: 149.3 °C
Boiling Point: 323.3 °C at 760 mmHg
Product Categories about Nitroguanidine (CAS NO.556-88-7) are Guanidines ; Nitrogen Compounds ; Organic Building Blocks
The chemical synonymous of are Labotest-Bb Ltbb000482 ; [Oxido(oxo)hydrazono]methanediamine ; 1-Nitro-guanidin ; Nitroguanidine ; 2-Nitroguanidine ; Alpha-nitroguanidine ; Beta-nitroguanidine ; Guanidine, 1-nitro- 

Nitroguanidine Uses

 Nitroguanidine (CAS NO.556-88-7) is used for the preparation of explosives.

Nitroguanidine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 3120mg/kg (3120mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.
mouse LD50 intraperitoneal 48mg/kg (48mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Pharmaceutical Chemistry Journal Vol. 10, Pg. 1504, 1976.
mouse LD50 oral 3850mg/kg (3850mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.
rabbit LD skin > 2gm/kg (2000mg/kg)   National Technical Information Service. Vol. AD-A191-796,
rat LD50 oral 10200mg/kg (10200mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(1), Pg. 18, 1980.

Nitroguanidine Consensus Reports

Reported in EPA TSCA Inventory.

Nitroguanidine Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or by chemical reaction with oxidizers. A severe explosion hazard when shocked or exposed to heat or flame. It is about as powerful as TNT. It is normally mixed with colloided nitrocellulose or ammonium nitrate and paraffin wax. Can react vigorously with oxidizing materials and the derivatives can be explosive. The mercury and silver salts and other derivatives are much more impact-sensitive. When heated to decomposition it emits highly toxic fumes of NOx. See also NITRO COMPOUNDS.
Hazard Codes:
F: Flammable
Xi: Irritant
Risk Statements about Nitroguanidine (CAS NO.556-88-7):
R5 Heating may cause an explosion.
R11 Highly flammable. 
R36/37/38 Irritating to eyes, respiratory system and skin. 
Safety Statements about α-Nitroguanidine (CAS NO.556-88-7):
S16 Keep away from sources of ignition - No smoking. 
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39 Wear suitable gloves and eye/face protection. 
S47 Keep at temperature not exceeding ...°C (to be specified by the manufacturer).

Nitroguanidine Standards and Recommendations

DOT Classification:  EXPLOSIVE 1.1D; Label: EXPLOSIVE 1.1D (UN 0282); DOT Class: 4.1; Label: Flammable Solid (UN 1336)

Nitroguanidine Specification

 Attention:
1. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
2. Handling: Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

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