- 5080-22-82-Propanamine,N-hydroxy-
- 50802-52-3Benzoic acid,4-pentyl-, 4-(hexyloxy)phenyl ester
- 50803-29-73-Chlorosulfonyl-4-methoxybenzoic acid
- 508-04-313(18)-Oleanen-3-ol
- 5080-50-21-Propanaminium,2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride (1:1), (2R)-
- 50807-74-4Propane,1,1,1,2,2-pentafluoro-3-(1,1,2,2-tetrafluoroethoxy)-
- 508-09-8Glutinone (triterpene)
- 50811-90-0Molybdate(6-),hexatriaconta-m-oxooctadecaoxobis[m9-[phosphato(3-)-O:O:O:O':O':O'':O'':O''':O''']]octadeca-,hexasodium (9CI)
- 50812-17-4Galactomannanase
- 50812-33-4Proteinase inhibitor,potato, IIb (9CI)
Hot Products
- 50809-32-0THYROID, PORCINE
- 50813-16-6SODIUM POLYPHOSPHATE
- 50858-51-0POLY(PROPYLENE GLYCOL) ACRYLATE
- 50862-68-5Guanidine, cyano-, polymer with N-(2-aminoethyl)-1,2-ethanediamine
- 5086-74-8Tetramisole hydrochloride
- 50887-69-9Orotic acid monohydrate
- 509-14-8TETRANITROMETHANE
- 509-34-2Solvent Red 49
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Oleanic acid |
EINECS | 208-081-6 |
| CAS No. | 508-02-1 | Density | 1.1 g/cm3 |
| PSA | 57.53000 | LogP | 7.23360 |
| Solubility | N/A | Melting Point |
>300 °C |
| Formula | C30H48O3 | Boiling Point | 553.5 °C at 760 mmHg |
| Molecular Weight | 456.709 | Flash Point | 302.6 °C |
| Transport Information | N/A | Appearance | light yellow |
| Safety | 26-36 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
3-beta-Hydroxyolean-12-en-28-oic acid;Olean-12-en-28-oic acid, 3-beta-hydroxy- (8CI);(4aS,5S,6aS,6bR,8R,8aR,10S,12aR,12bR,14bS)-10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid;Giganteumgenin C;Olean-12-en-28-oic acid,3-hydroxy-,(3a)-;Olean-12-en-28-oic acid, 3-hydroxy-, (3.beta.)-;Virgaureagenin B;Caryophyllin;Astrantiagenin C; |
Article Data | 103 |
Oleanic acid Synthetic route
- 152487-68-8
(4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(tert-Butyl-dimethyl-silanyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With tetrabutyl ammonium fluoride In tetrahydrofuran at 55℃; for 13h; | 96% |
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With titanium tetrachloride In dichloromethane at 20℃; for 0.5h; solid phase reaction; | 94.6% |
A
- 1310058-25-3
3β-[(E)-3-(thiophen-2-yl)acryloxyl]-olean-12-en-28-oic acid
B
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With titanium tetrachloride In dichloromethane at 20℃; for 0.5h; solid phase reaction; | A 92% B 0.5 mg |
- 1310058-23-1
{2-[2-(triphenylmethyl)aminoethoxy]ethoxy}methyl olean-12-en-28-oate
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With titanium tetrachloride In dichloromethane at 20℃; for 0.5h; | 89.6% |
- 25493-69-0, 122798-61-2, 1721-57-9
(4aS,6aS,6bR,10S,12aR)-methyl 10-acetoxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With Me2AlTeMe In toluene at 50℃; for 10h; | 80% |
- 1724-17-0, 73584-64-2
oleanolic acid methyl ester
- 508-02-1
Oleanolic acid
| Conditions | Yield |
|---|---|
| With lithium In ethylenediamine for 4h; Heating; | 70% |
| With lithium In ethylenediamine for 4h; Heating; other hindered esters; | 70% |
- 86532-12-9
3β-acetyl-12α-bromo-oleanan-28 <*> 13β-olide
A
- 508-02-1
Oleanolic acid
B
- 17990-43-1
3-dehydroxy-oleanolic acid
| Conditions | Yield |
|---|---|
| With lithium; ethylenediamine for 2h; Heating; | A 35% B 30% |
- 77-52-1
ursolic acid
A
- 508-02-1
Oleanolic acid
B
- 915-32-2, 26532-60-5, 32208-45-0, 74984-68-2, 94482-47-0, 121468-30-2
methyl (3β)-3-hydroxyurs-12-en-28-oate
C
- 1724-17-0, 73584-64-2
oleanolic acid methyl ester
| Conditions | Yield |
|---|---|
| at 28℃; for 120h; pH=7.0; Product distribution; Microbiological reaction; | A 21% B 9% C 13% |
| Conditions | Yield |
|---|---|
| at 180℃; im Rohr; |
| Conditions | Yield |
|---|---|
| at 160 - 170℃; im Rohr; |
Oleanic acid Chemical Properties
IUPAC Name: 10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
Synonyms of Oleanolic acid (CAS NO.508-02-1): 3Beta-Hydroxyolean-12-en-28-oic acid
Molecular Structure: 
Molecular Formula: C30H48O3
Molecular Weight: 456.71
CAS NO: 508-02-1
H bond acceptors: 3
H bond donors: 2
Freely Rotating Bonds: 2
Polar Surface Area: 35.53 Å2
Index of Refraction: 1.557
Molar Refractivity: 133.57 cm3
Molar Volume: 414.9 cm3
EINECS : 208-081-6
Mol File: 508-02-1.mol
Melting point: >300°C
Storage temp: 2-8°C
Surface Tension: 45.4 dyne/cm
Density: 1.1 g/cm3
Flash Point: 302.6 °C
Enthalpy of Vaporization: 95.9 kJ/mol
Boiling Point: 553.5 °C at 760 mmHg
Vapour Pressure: 1.47E-14 mmHg at 25°C
Color: light yellow.
Product Categories of Oleanolic acid (CAS NO.508-02-1): Pentacyclic triterpenes;Tri-Terpenoids;Biochemistry;Terpenes;Terpenes (Others);Natural Plant Extract;Anti-proliferative AgentsAsymmetric Synthesis;Complex MoleculesNutrition Research;Isoprenoid/terpenoidCancer Research;Phase I Enzyme Inhibitors;Phase I Enzyme InhibitorsCancer Research;Biochemicals Found in Plants;Cancer Research;Chemopreventive Agents;Chiral Building Blocks;Multidrug Resistance
Oleanic acid Uses
Oleanolic acid (CAS NO.508-02-1) is suitable for all types of hepatitis, with the promotion of liver regeneration to accelerate the repair of damaged liver cells, and has a strong effects on heart, diuretic and anti-inflammatory.
Oleanic acid Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 1500mg/kg (1500mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 44, Pg. 456, 1992. | |
| mouse | LD50 | oral | > 2gm/kg (2000mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 44, Pg. 456, 1992. | |
| rat | LD50 | intraperitoneal | > 2gm/kg (2000mg/kg) | Drugs of the Future. Vol. 19, Pg. 450, 1994. | |
| rat | LD50 | oral | > 2gm/kg (2000mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 44, Pg. 456, 1992. |
Oleanic acid Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38: Oleanolic acid (CAS NO. 508-02-1) is irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 2
RTECS: RK0177965
Oleanic acid Specification
Oleanolic acid (CAS NO.508-02-1) is a naturally occurring triterpenoid, which distributed in food and medicinal plants, related to betulinic acid. And it can be widely found in Phytolacca americana (American pokeweed), and Syzygium spp, garlic, etc. It is quite non-toxic, antitumor, and hepatoprotective, as well as exhibiting antiviral properties.
What can I do for you?
Get Best Price
