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Name |
Pheniramine |
EINECS | 201-656-2 |
CAS No. | 86-21-5 | Density | 1.018 g/cm3 |
PSA | 16.13000 | LogP | 3.16520 |
Solubility | N/A | Melting Point |
30-34°C(lit.) |
Formula | C16H20 N2 | Boiling Point | 348.3 °C at 760 mmHg |
Molecular Weight | 240.348 | Flash Point | 164.5 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intravenous route. Human systemic effects by ingestion: central nervous system effects. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | 11-23/24/25-39/23/24/25 |
Molecular Structure | Hazard Symbols | F,T | |
Synonyms |
Pyridine,2-[a-[2-(dimethylamino)ethyl]benzyl]-(8CI); (?à)-Pheniramine;1-Phenyl-1-(2-pyridyl)-3-di-methylaminopropane; 2-[a-(2-Dimethylaminoethyl)benzyl]pyridine;3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine; NSC 47965; Pheniramine;Propheniramine; Prophenpyridamine; Pyriton; Tripoton |
Article Data | 26 |
Conditions | Yield |
---|---|
With hydrogen; platinum(IV) oxide In toluene at 120℃; under 38000 Torr; for 12h; catalytic reductive amination; | 100% |
Conditions | Yield |
---|---|
(η5-cyclopentadienyl)-η4-cycloocta-1,5-dienecobalt(I) In toluene at 140℃; under 10640 Torr; for 36h; | 85% |
Conditions | Yield |
---|---|
With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; bis[2-(diphenylphosphino)phenyl] ether In toluene at 20℃; Inert atmosphere; Reflux; | 84% |
2-(1-phenylvinyl)pyridine
carbon monoxide
dimethyl amine
pheniramine
Conditions | Yield |
---|---|
With hydrogen; [Rh(1,3-dimesitylimidazole-2-ylidene)(cod)Cl] In toluene at 125℃; for 24h; | 80% |
pheniramine
Conditions | Yield |
---|---|
With methylmagnesium bromide In tetrahydrofuran; diethyl ether at 20℃; | 42% |
Conditions | Yield |
---|---|
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 0.8C12H6N2O4(2-)*HO(1-)*Al(3+)*0.4CF3O3S(1-)*0.1Ir(3+)*0.2C11H8N(1-)*0.1Cl(1-) In acetonitrile at 20℃; for 6h; Inert atmosphere; Irradiation; | 38% |
Conditions | Yield |
---|---|
With sodium amide; benzene anschl. mit <2-Chlor-aethyl>-dimethyl-amin und anschl. Erhitzen mit KOH in Butan-1-ol; |
Conditions | Yield |
---|---|
With potassium amide | |
With sodium | |
With sodium amide | |
With potassium amide |
Conditions | Yield |
---|---|
With sodium amide; toluene anschl. mit <2-Chlor-aethyl>-dimethyl-amin und anschl. Erwaermen mit H2SO4; |
dimethyl-(3-phenyl-3-pyridin-2-yl-allyl)-amine
pheniramine
Conditions | Yield |
---|---|
With palladium on activated charcoal; acetic acid Hydrogenation; | |
With nickel Hydrogenation; | |
With palladium on activated charcoal; acetic acid Hydrogenation; |
IUPAC Name: N,N-Dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
The MF of Pheniramine (CAS NO.86-21-5) is C16H20N2.
The MW of Pheniramine (CAS NO.86-21-5) is 240.34.
Synonyms of Pheniramine (CAS NO.86-21-5): Pheniramine ; 2-[.alpha.-[2-(Dimethylamino)ethyl]benzyl]pyridine ; 2-Pyridinepropanamine, N,N-dimethyl-.gamma.-phenyl
Index of Refraction: 1.556
EINECS: 201-656-2
Density: 1.018 g/ml
Flash Point: 164.5 °C
Boiling Point: 348.3 °C
Pheniramine (CAS NO.86-21-5) is used as chemical reagent, fine chemicals, organic synthesis reagents, pharmaceutical intermediates.
1. | orl-wmn TDLo:14 mg/kg:CNS | MJAUAJ Medical Journal of Australia. 2 (3)(1976),110. | ||
2. | ivn-mus LD50:48 mg/kg | AEPPAE Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 211 (1950),328. | ||
3. | ivn-rbt LDLo:30 mg/kg | AEPPAE Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 211 (1950),328. |
Poison by intravenous route. Human systemic effects by ingestion: central nervous system effects. When heated to decomposition it emits toxic fumes of NOx.