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Potassium antimonyl tartrate sesquihydrate

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Potassium antimonyl tartrate sesquihydrate

EINECS 234-293-3
CAS No. 28300-74-5 Density 2.607 g/cm3
PSA 151.35000 LogP -2.66350
Solubility water: 8.3 g/100 mL Melting Point ≥300 °C(lit.)
Formula C8H4K2O12Sb2.3(H2O) Boiling Point N/A
Molecular Weight 667.87 Flash Point N/A
Transport Information UN 1551 6.1/PG 3 Appearance colourless crystals
Safety 61 Risk Codes 20/22-51/53
Molecular Structure Molecular Structure of 28300-74-5 (Potassium antimonyl tartrate sesquihydrate) Hazard Symbols HarmfulXn,DangerousN

Antimonate(2-),bis[m-[2,3-di(hydroxy-kO)butanedioato(4-)-kO1:kO4]]di-, dipotassium, trihydrate, stereoisomer (9CI);Antimonate(2-), bis[m-tartrato(4-)]di-, dipotassium, trihydrate (8CI);Antimonate(1-),aqua[tartrato(4-)]-, potassium, sesquihydrate, dimer;Antimony potassium tartrate;Antimonyl potassium tartrate, sesquihydrate;Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, antimony potassium salt;Potassium antimony tartrate;Tartaremetic;Tartox;


Potassium antimonyl tartrate sesquihydrate Chemical Properties

Empirical Formula: C8H10K2O15Sb2
Molecular Weight: 667.8726 g/mol
Melting point: ≥300 °C(lit.)
Water solubility: 8.3 g/100 mL
Appearance: Colourless crystals
Structure of Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5):
Product Category of Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5): Industrial/Fine Chemicals;Organometallics

Potassium antimonyl tartrate sesquihydrate Uses

 Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) can be used for anti-blood-sucking insects drugs added to animal feed.

Potassium antimonyl tartrate sesquihydrate Production

The product can be derived from tartaric acid by via antimonide. Take the mixture of four copies of Antimony trioxide , and 5 copies of Potassium hydrogen tartrate into 40 copies of hot water. While stirring while heating, so that the most dissolved and still hot filtration, and then cooling and crystallization. Filtration and then refined for re-crystallization.

Potassium antimonyl tartrate sesquihydrate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 15mg/kg (15mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
guinea pig LDLo intramuscular 55mg/kg (55mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human LDLo oral 2mg/kg (2mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1097, 1966.
Lancet. Vol. 210, Pg. 227, 1926.
man LD50 intravenous 249mg/kg/9D-I (249mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
Journal of Tropical Medicine and Hygiene. Vol. 21, Pg. 38, 1918.
man LDLo intravenous 12mg/kg/1W-I (12mg/kg) LIVER: OTHER CHANGES
Lancet. Vol. 210, Pg. 227, 1926.
mouse LD50 intraperitoneal 33mg/kg (33mg/kg)   Bulletin of the World Health Organization. Vol. 53, Pg. 379, 1976.
mouse LD50 intravenous 45mg/kg (45mg/kg)   Fortschritte der Arzneimittelforschung. Progress in Drug Research. Vol. 17, Pg. 108, 1973.
mouse LD50 subcutaneous 55mg/kg (55mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

Proceedings of the Society for Experimental Biology and Medicine. Vol. 129, Pg. 284, 1968.
mouse LDLo oral 600mg/kg (600mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit LD50 intravenous 12mg/kg (12mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 196, 1947.
rabbit LD50 oral 115mg/kg (115mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intraperitoneal 11mg/kg (11mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 oral 115mg/kg (115mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 24, 1966.
rat LDLo intramuscular 33mg/kg (33mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

 Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

Potassium antimonyl tartrate sesquihydrate Consensus Reports

Antimony and its compounds are on the Community Right-To-Know List.

Potassium antimonyl tartrate sesquihydrate Safety Profile

Human poison by intravenous route, producing liver and kidney changes, somnolence, dyspnea, and pupillary dilation. Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Large doses cause severe liver damage. Human mutation data reported. Used medicinally, the therapeutic dose is close to the toxic dose. Upon decomposition it emits toxic fumes of K2O and Sb.
Hazard Codes: HarmfulXn,DangerousN
Risk Statements: 20/22-51/53 
R20/22:Harmful by inhalation and if swallowed. 
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 61 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.

Potassium antimonyl tartrate sesquihydrate Standards and Recommendations

OSHA PEL: TWA 0.5 mg(Sb)/m3
ACGIH TLV: TWA 0.5 mg(Sb)/m3
NIOSH REL: (Antimony) TWA 0.5 mg(Sb)/m3
DOT Classification:  6.1; Label: KEEP AWAY FROM FOOD

Potassium antimonyl tartrate sesquihydrate Specification

 Potassium antimonyl tartrate sesquihydrate , its cas register number is 28300-74-5. It also can be called Antimony potassium tartrate trihydrate ; and Antimonate(2-), bis(mu-(2,3-dihydroxybutanedioato(4-)-O1,O2:O3,O4))di-, dipotassium, trihydrate, stereoisomer . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Get medical aid if irritation develops or persists. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid
In addition, Potassium antimonyl tartrate sesquihydrate (CAS NO.28300-74-5) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, acids, bases, carbonates, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide, antimony/antimony oxides, oxides of potassium.

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