4-(1-Amino-2,2,2-trifluoroethyl)phenol

Base Information

Chemical Name:4-(1-Amino-2,2,2-trifluoroethyl)phenol
CAS No.:294175-07-8
Molecular Formula:C₈H₈F₃NO
Molecular Weight:191.153
Hs Code.:2922500090
European Community (EC) Number:808-736-1
DSSTox Substance ID:DTXSID50462614
Nikkaji Number:J1.336.432J
Mol file:294175-07-8.mol

Synonyms:4-(1-amino-2,2,2-trifluoroethyl)phenol;294175-07-8;4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol;Phenol, 4-(1-amino-2,2,2-trifluoroethyl)-;1187928-59-1;MFCD09832191;1187930-88-6;(R)-4-(1-amino-2,2,2-trifluoroethyl)phenol;(S)-4-(1-amino-2,2,2-trifluoroethyl)phenol;(R)-4-(1-AMINO-2,2,2-TRIFLUORO-ETHYL)-PHENOL;SCHEMBL23646685;DTXSID50462614;XIBJQYMKBQZQPP-UHFFFAOYSA-N;AKOS015917204;SB31219;SB31384;SB36422;AS-77039;SY028934;CS-0005297;FT-0751907;EN300-1939389;A876475;4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol, AldrichCPR;4-(1-Amino-2,2,2-trifluorethyl)phenol;phenol, 4-(1-amino-2,2,2-trifluoroethyl)-;LogP

Suppliers and Price of 4-(1-Amino-2,2,2-trifluoroethyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1-Amino-2,2,2-trifluoroethyl)phenol
5mg
$ 45.00

SynQuest Laboratories
4-(1-Amino-2,2,2-trifluoroethyl)phenol 96%
250 mg
$ 791.00

SynQuest Laboratories
4-(1-Amino-2,2,2-trifluoroethyl)phenol 96%
1 g
$ 2128.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
5g
$ 3998.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
1g
$ 998.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
250mg
$ 325.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
100mg
$ 212.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
50mg
$ 156.00

J&W Pharmlab
4-(1-Amino-2,2,2-trifluoro-ethyl)-phenol 96%
500mg
$ 549.00

Crysdot
4-(1-Amino-2,2,2-trifluoroethyl)phenol 95+%
1g
$ 518.00

Total 8 raw suppliers

Chemical Property of 4-(1-Amino-2,2,2-trifluoroethyl)phenol

Chemical Property:

Vapor Pressure:0.00603mmHg at 25°C
Boiling Point:264.2oC at 760 mmHg
Flash Point:113.6oC
PSA：46.25000
Density:1.35g/cm3
LogP:2.65460
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:191.05579836
Heavy Atom Count:13
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

4-(1-Amino-2,2,2-trifluoroethyl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(F)(F)F)N)O

Technology Process of 4-(1-Amino-2,2,2-trifluoroethyl)phenol

There total 3 articles about 4-(1-Amino-2,2,2-trifluoroethyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 294175-02-3
4-[1-(benzhydrylamino)-2,2,2-trifluoroethyl]phenol

: 294175-07-8
1-(4-Hydroxyphenyl)-2,2,2-trifluoroethylamine

Guidance literature:: With hydrogenchloride; for 36h; Heating;

Reference yield: 51.0%

: 75-90-1
2,2,2-Trifluoroacetaldehyde

: 108-95-2,27073-41-2
phenol

: 246245-20-5
2,2,2-trifluoro-1-(4-hydroxyphenyl)ethyl alcohol

: 294175-07-8
1-(4-Hydroxyphenyl)-2,2,2-trifluoroethylamine

Guidance literature:: 2,2,2-Trifluoroacetaldehyde; With 1,1,1,3,3,3-hexamethyl-disilazane; In dichloromethane; at -70 ℃; for 0.5h;

phenol; With aluminium trichloride; In dichloromethane; at 10 ℃; for 18h;
DOI:10.1016/S0022-1139(02)00044-1