4-Chloro-N-phenylbenzohydroxamic acid

Base Information

• Chemical Name: 4-Chloro-N-phenylbenzohydroxamic acid
• CAS No.: 29556-28-3
• Molecular Formula: C13H10ClNO2
• Molecular Weight: 247.681
• European Community (EC) Number: 632-564-4
• Nikkaji Number: J582.815E
• Mol file: 29556-28-3.mol

Synonyms:4-Chloro-N-phenylbenzohydroxamic acid;AKOS024337705

Chemical Property of 4-Chloro-N-phenylbenzohydroxamic acid

Chemical Property:

• Vapor Pressure: 1.8E-07mmHg at 25°C
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 247.0400063
• Heavy Atom Count: 17
• Complexity: 258

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N(C(=O)C2=CC=C(C=C2)Cl)O

Technology Process of 4-Chloro-N-phenylbenzohydroxamic acid

There total 5 articles about 4-Chloro-N-phenylbenzohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-chloro-benzoyl chloride (122-01-0) + N-Phenylhydroxylamine (100-65-2) → N-phenyl-p-chlorobenzohydroxamic acid (29556-28-3)

Guidance literature:

With sodium hydrogencarbonate; In water; at 0 - 5 ℃; for 2h;

DOI:10.1134/S0036023611110192

Reference yield:

4-chlorobenzaldehyde (104-88-1) + nitrobenzene (98-95-3,26969-40-4) → 4-chlorobenzanilide (6833-15-4) + N-phenyl-p-chlorobenzohydroxamic acid (29556-28-3)

Guidance literature:

With manganese(IV) oxide; potassium hydroxide; at 120 ℃; for 48h; Inert atmosphere;

DOI:10.1039/c4ob01155d

Reference yield:

4-chlorobenzaldehyde (104-88-1) + Nitrosobenzene (586-96-9) → N-phenyl-p-chlorobenzohydroxamic acid (29556-28-3)

Guidance literature:

With 2-pentafluorophenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; N,N,N,N,-tetramethylethylenediamine; In dichloromethane; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/asia.201300938

upstream raw materials:

4-chloro-benzoyl chloride

N-Phenylhydroxylamine

4-chlorobenzaldehyde

Nitrosobenzene

Downstream raw materials:

N-Phenylhydroxylamine

para-chlorobenzoic acid

sodium p-chlorobenzoate

MoO₂(ON(C₆H₅)CO(C₆H₄Cl))2