1-Acetyl-3-benzylidene-2,5-piperazinedione

Base Information

Chemical Name:1-Acetyl-3-benzylidene-2,5-piperazinedione
CAS No.:30166-30-4
Molecular Formula:C₁₃H₁₂N₂O₃
Molecular Weight:244.25
Hs Code.:
DSSTox Substance ID:DTXSID20396033
Mol file:30166-30-4.mol

Synonyms:1-ACETYL-3-BENZYLIDENE-PIPERAZINE-2,5-DIONE;30166-29-1;1-acetyl-3-benzylidene-2,5-piperazinedione;DTXSID20396033;MJCOATFQVUUHFN-UHFFFAOYSA-N;AKOS030237621;1-acetyl-3-benzylidene piperazine-2,5-dione

Suppliers and Price of 1-Acetyl-3-benzylidene-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-Acetyl-3-benzylidene-2,5-piperazinedione

Chemical Property:

PSA：69.97000
LogP:0.74620
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:244.08479225
Heavy Atom Count:18
Complexity:409

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N1CC(=O)NC(=CC2=CC=CC=C2)C1=O

Technology Process of 1-Acetyl-3-benzylidene-2,5-piperazinedione

There total 5 articles about 1-Acetyl-3-benzylidene-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 100-52-7
benzaldehyde

: 30166-29-1,30166-30-4,41808-11-1
1-acetyl-3-[(Z)-benzylidene]-2,5-piperazinedione

Guidance literature:: With potassium tert-butylate; tert-butyl alcohol; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1081/SCC-120030746

Reference yield: 57.7%

: 108-24-7
acetic anhydride

: 19459-03-1
(Z)-3-phenylmethylenepiperazine-2,5-dione

: 30166-29-1,30166-30-4,41808-11-1
1-acetyl-3-[(Z)-benzylidene]-2,5-piperazinedione

: 68662-68-0
1,4-diacetyl-(Z)-3-benzylidene-2,5-piperazinedione

Guidance literature:: at 130 ℃; for 0.5h;

Reference yield: 33.0%

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 100-52-7
benzaldehyde

: 106-95-6
allyl bromide

: C₁₆H₁₆N₂O₃

: 30166-29-1,30166-30-4,41808-11-1
1-acetyl-3-[(Z)-benzylidene]-2,5-piperazinedione

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Reagent/catalyst; Molecular sieve; Inert atmosphere;
DOI:10.1016/j.tet.2015.12.073