4-Iodo-N-(4-methoxybenzylidene)aniline

Base Information

• Chemical Name: 4-Iodo-N-(4-methoxybenzylidene)aniline
• CAS No.: 3381-49-5
• Molecular Formula: C14H12INO
• Molecular Weight: 337.16
• Hs Code.: 2925290090
• European Community (EC) Number: 666-167-2
• Mol file: 3381-49-5.mol

Synonyms:4-Iodo-N-(4-methoxybenzylidene)aniline;SCHEMBL20871788;AKOS003407877;(4-iodophenyl)(4-methoxybenzylidene)amine

Chemical Property of 4-Iodo-N-(4-methoxybenzylidene)aniline

Chemical Property:

• PSA: 21.59000
• LogP: 4.05040
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 336.99636
• Heavy Atom Count: 17
• Complexity: 241

Purity/Quality:

95% ^*data from raw suppliers

4-IODO-N-(4-METHOXYBENZYLIDENE)ANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=NC2=CC=C(C=C2)I

Technology Process of 4-Iodo-N-(4-methoxybenzylidene)aniline

There total 4 articles about 4-Iodo-N-(4-methoxybenzylidene)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ p-methoxybenzylidene-4-iodoaniline (3381-49-5)

Guidance literature:

Reference yield:

p-nitrobenzene iodide (636-98-6) + 4-methoxy-benzaldehyde (123-11-5) → N-(4'-methoxybenzyl)-4-iodoaniline (1039968-13-2) + p-methoxybenzylidene-4-iodoaniline (3381-49-5)

Guidance literature:

With C₂₉H₃₈ClN₅O₂Ru; hydrogen; In isopropyl alcohol; at 40 - 80 ℃; for 16h; under 1125.11 - 3750.38 Torr;

DOI:10.1016/j.jcat.2012.04.015

Reference yield:

4-methoxy-benzylamine (2393-23-9) + p-aminoiodobenzene (540-37-4) → p-methoxybenzylidene-4-iodoaniline (3381-49-5)

Guidance literature:

With cobalt nanoparticles encapsulated within nitrogen doped graphitic shells prepared via pyrolysis of poly([1,3-bis(4-vinylbenzyl)imidazolium]CoCl₄) at 800 ^oC; In toluene; at 120 ℃; for 20h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1002/anie.201915526

upstream raw materials:

4-methoxy-benzaldehyde

p-aminoiodobenzene

p-nitrobenzene iodide

4-methoxy-benzylamine