Benzenepropanoic acid, b-methylene-, methyl ester

Base Information

• Chemical Name: Benzenepropanoic acid, b-methylene-, methyl ester
• CAS No.: 3461-38-9
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Hs Code.: 2916399090
• Mol file: 3461-38-9.mol

Synonyms:Methyl 3-phenyl-3-butenoate;methyl 3-phenyl-3-butenoic acid;methyl 3-phenyl-but-3-enoate;3-phenyl-but-3-enoic acid methyl ester;3-Phenyl-but-3-ensaeure-methylester;

Chemical Property of Benzenepropanoic acid, b-methylene-, methyl ester

Chemical Property:

• Boiling Point: 260.0±9.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.026±0.06 g/cm3(Predicted)
• LogP: 2.26290

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenepropanoic acid, b-methylene-, methyl ester

There total 25 articles about Benzenepropanoic acid, b-methylene-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3-phenylbut-3-enoic acid (5155-87-3) → 3-methylenebenzenepropanoic acid methyl ester (3461-38-9)

Guidance literature:

DOI:10.1016/0022-328X(89)87295-X

Reference yield: 83.0%

methanol (67-56-1) + carbon monoxide (201230-82-2) + isopropenylbenzene (98-83-9,6144-04-3,25014-31-7,42612-14-6) → 3-methylenebenzenepropanoic acid methyl ester (3461-38-9)

Guidance literature:

With palladium diacetate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In acetonitrile; at 50 ℃; for 24h; under 760.051 Torr; regioselective reaction;

DOI:10.1039/c1cc15781g

Reference yield: 76.0%

methanol (67-56-1) + 3-phenylbut-3-enoic acid (5155-87-3) → 3-methylenebenzenepropanoic acid methyl ester (3461-38-9)

Guidance literature:

With sulfuric acid; for 0.5h; Heating;

DOI:10.1246/bcsj.64.3746

upstream raw materials:

methyl but-3-enoate

phenylmercuric acetate

methanol

carbon monoxide

Downstream raw materials:

3-phenyl-1-butanol

3-phenylbut-3-en-1-ol

3-phenyl-butyric acid methyl ester

formaldehyd