2-(Dimethylcarbamoyl)acetic acid

Base Information

Chemical Name:2-(Dimethylcarbamoyl)acetic acid
CAS No.:42783-81-3
Molecular Formula:C5H9NO3
Molecular Weight:131.131
Hs Code.:
European Community (EC) Number:837-767-3
DSSTox Substance ID:DTXSID701288234
Nikkaji Number:J1.822.026A
Mol file:42783-81-3.mol

Synonyms:2-(dimethylcarbamoyl)acetic acid;42783-81-3;3-(dimethylamino)-3-oxopropanoic acid;MFCD06208070;3-(dimethylamino)-3-oxo-propanoic acid;propanoic acid, 3-(dimethylamino)-3-oxo;Propanoic acid, 3-(dimethylamino)-3-oxo-;malonic acid bismethylamide;SCHEMBL53024;AKDXGMLXZNIGBD-UHFFFAOYSA-N;N,N-Dimethyl-3-oxo-Beta-alanine;DTXSID701288234;3-(dimethylamino)-3-oxopropanoicacid;AKOS008153595;BS-13114;SY195867;CS-0264633;EN300-93573;E88330;Z963467438

Suppliers and Price of 2-(Dimethylcarbamoyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(Dimethylcarbamoyl)acetic acid

Chemical Property:

XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:131.058243149
Heavy Atom Count:9
Complexity:130

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C(=O)CC(=O)O

Technology Process of 2-(Dimethylcarbamoyl)acetic acid

There total 1 articles about 2-(Dimethylcarbamoyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 40052-13-9
mono-tert-butyl malonate

: 124-40-3
dimethyl amine

: 42783-81-3
3-(dimethylamino)-3-oxopropanoic acid

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1016/j.bmc.2020.115541

Reference yield: 56.0%

: 42783-81-3
3-(dimethylamino)-3-oxopropanoic acid

: 103-80-0
phenylacetyl chloride

: N,N-dimethyl 4-phenyl-3-oxobutanamide

Guidance literature:: 3-(dimethylamino)-3-oxopropanoic acid; With [2,2]bipyridinyl; n-butyllithium; In tetrahydrofuran; hexane; at -78 - -10 ℃;

phenylacetyl chloride; In tetrahydrofuran; hexane; for 0.5h;
DOI:10.1055/s-2002-34845

Reference yield: 34.0%

: 1188424-55-6
10-amino-N-(4-fluorobenzyl)-3-hydroxy-4-oxo-4,6,7,8,9,10-hexahydro-7,10-ethanopyrimido[1,2-a]azepine-2-carboxamide

: 42783-81-3
3-(dimethylamino)-3-oxopropanoic acid

: 1188424-80-7
N'-(2-((4-fluorobenzyl)carbamoyl)-3-hydroxy-4-oxo-6,7,8,9-tetrahydro-7,10-ethanopyrimido[1,2-a]azepin-10(4H)-yl)-N,N-dimethylpropanediamide

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmc.2020.115541