O,S-Dimethyl N,N-dimethylphosphoramidothioate

Base Information

• Chemical Name: O,S-Dimethyl N,N-dimethylphosphoramidothioate
• CAS No.: 25218-42-2
• Molecular Formula: C₄H₁₂NO₂PS
• Molecular Weight: 169.185
• NSC Number: 133030
• Mol file: 25218-42-2.mol

Synonyms:O,S-Dimethyl N,N-dimethylphosphoramidothioate;NSC133030;MHMGPLAZDGAJDI-UHFFFAOYSA-N;NSC-133030;25218-42-2

Chemical Property of O,S-Dimethyl N,N-dimethylphosphoramidothioate

Chemical Property:

• Vapor Pressure: 0.364mmHg at 25°C
• Boiling Point: 198.2°Cat760mmHg
• Flash Point: 73.7°C
• Density: 1.156g/cm³
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 169.03263680
• Heavy Atom Count: 9
• Complexity: 128

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(=O)(OC)SC

Technology Process of O,S-Dimethyl N,N-dimethylphosphoramidothioate

There total 3 articles about O,S-Dimethyl N,N-dimethylphosphoramidothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-methyl O,O-dimethyl phosphoramidothioate (31464-99-0) + dimethyl amine (124-40-3) + methyl iodide (74-88-4) → N,N-dimethyl O,S-dimethyl phosphoramidothioate (65960-94-3,87000-69-9,25218-42-2)

Guidance literature:

With 18-crown-6 ether; potassium iodide; In dichloromethane; acetonitrile; at 80 ℃;

DOI:10.1007/BF03245903

Reference yield:

N,N-dimethyl O,O-dimethyl phosphoramidothioate (28167-51-3) + methyl iodide (74-88-4) → N,N-dimethyl O,S-dimethyl phosphoramidothioate (65960-94-3,87000-69-9,25218-42-2)

Guidance literature:

With potassium iodide; In chloroform; acetonitrile; at 70 ℃;

DOI:10.1007/BF03245903

Reference yield:

→ N,N-dimethyl O,S-dimethyl phosphoramidothioate (65960-94-3,87000-69-9,25218-42-2)

Guidance literature:

O,O-Dimethyl-N-dimethylphosphoramidothioat, MeI (Δ);

DOI:10.1021/jf60192a013

upstream raw materials:

N-methyl O,O-dimethyl phosphoramidothioate

dimethyl amine

methyl iodide

N,N-dimethyl O,O-dimethyl phosphoramidothioate

Downstream raw materials:

O,O,S-trimethyl phosphorothioate