O,O-Dimethyl N,N-dimethylphosphoramidothioate

Base Information

• Chemical Name: O,O-Dimethyl N,N-dimethylphosphoramidothioate
• CAS No.: 28167-51-3
• Molecular Formula: C4H12 N O2 P S
• Molecular Weight: 169.1823
• NSC Number: 133027
• DSSTox Substance ID: DTXSID20950912
• Nikkaji Number: J1.613.857F
• Wikidata: Q82929106
• Mol file: 28167-51-3.mol

Synonyms:O,O-Dimethyl N,N-dimethylphosphoramidothioate;28167-51-3;NSC133027;SCHEMBL13379822;DTXSID20950912;IGEJGDZWYDZEHX-UHFFFAOYSA-N;AKOS024359983;NSC-133027

Chemical Property of O,O-Dimethyl N,N-dimethylphosphoramidothioate

Chemical Property:

• Vapor Pressure: 2.04mmHg at 25°C
• Boiling Point: 163.7°C at 760 mmHg
• Flash Point: 52.8°C
• Density: 1.154g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 169.03263680
• Heavy Atom Count: 9
• Complexity: 120

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(=S)(OC)OC

Technology Process of O,O-Dimethyl N,N-dimethylphosphoramidothioate

There total 6 articles about O,O-Dimethyl N,N-dimethylphosphoramidothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N,N-dimethylammonium chloride (506-59-2) + dimethyl chlorothiophosphate (2524-03-0) → N,N-dimethyl O,O-dimethyl phosphoramidothioate (28167-51-3)

Guidance literature:

In dichloromethane; at 0 - 35 ℃; for 1h; pH=8.4 - 9.1;

DOI:10.1007/BF03245903

Reference yield:

dimethoxy(dimethylamino)phosphine (20217-54-3) → N,N-dimethyl O,O-dimethyl phosphoramidothioate (28167-51-3)

Guidance literature:

With sulfur;

Reference yield:

dimethyl-phosphoramidothioic dichloride (1498-65-3) + sodium methylate (124-41-4) → N,N-dimethyl O,O-dimethyl phosphoramidothioate (28167-51-3)

Guidance literature:

upstream raw materials:

dimethyl-phosphoramidothioic dichloride

sodium methylate

dimethyl chlorothiophosphate

dimethyl amine

Downstream raw materials:

N,N-dimethyl O,S-dimethyl phosphoramidothioate