Ethyl 2-(trimethylsilyl)propanoate

Base Information

Chemical Name:Ethyl 2-(trimethylsilyl)propanoate
CAS No.:13950-55-5
Molecular Formula:C₈H₁₈O₂Si
Molecular Weight:174.315
Hs Code.:
NSC Number:108053
DSSTox Substance ID:DTXSID20296160
Nikkaji Number:J483.839D
Mol file:13950-55-5.mol

Synonyms:13950-55-5;ethyl 2-(trimethylsilyl)propanoate;NSC108053;ethyl 2-trimethylsilylpropionate;SCHEMBL8112896;DTXSID20296160;ZIHQTRCBUOIWOE-UHFFFAOYSA-N;NSC-108053

Suppliers and Price of Ethyl 2-(trimethylsilyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethyl 2-(trimethylsilyl)propanoate

Chemical Property:

Vapor Pressure:1.86mmHg at 25°C
Boiling Point:165.5°Cat760mmHg
Flash Point:45.2°C
Density:0.87g/cm³
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:174.107606347
Heavy Atom Count:11
Complexity:138

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)[Si](C)(C)C

Technology Process of Ethyl 2-(trimethylsilyl)propanoate

There total 11 articles about Ethyl 2-(trimethylsilyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 75-77-4
chloro-trimethyl-silane

: 535-11-5,41978-69-2
Ethyl 2-bromopropionate

: 13950-55-5
ethyl 2-(trimethylsilyl)propionate

Guidance literature:: With dichlorobis(tri-O-tolylphosphine)palladium; bis(tri-n-butyltin); In N,N,N,N,N,N-hexamethylphosphoric triamide; at 80 ℃; for 20h;
DOI:10.1246/bcsj.58.1075

Reference yield:

: 4071-88-9
trimethylsilanyl-acetic acid ethyl ester

: 74-88-4
methyl iodide

: 13950-55-5
ethyl 2-(trimethylsilyl)propionate

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;
DOI:10.1021/jo00060a059

Reference yield:

: 64-17-5
ethanol

: 201230-82-2
carbon monoxide

: 754-05-2
ethenyltrimethylsilane

: 17728-88-0
ethyl 3-(trimethylsilyl)propionate

: 13950-55-5
ethyl 2-(trimethylsilyl)propionate

Guidance literature:: bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 90 ℃; for 16h; under 44130.5 Torr; Product distribution; Mechanism; other temperatures, other solvents, other Pd-, Pt- and/or Co-catalysts, other vinylsilanes; α- or β-regioselectivity/regiospecifity of hydroesterification;
DOI:10.1021/jo00041a025