4-Hydroxy-4-phenylcyclohexanone

Base Information

• Chemical Name: 4-Hydroxy-4-phenylcyclohexanone
• CAS No.: 51171-73-4
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Hs Code.: 2914400090
• Mol file: 51171-73-4.mol

Synonyms:4-Hydroxy-4-phenylcyclohexanon;4-Phenyl-4-hydroxycyclohexanon;4-Hydroxy-4-phenyl-cyclohexanon-(1);4-phenyl-4-hydroxycyclohexanone;Cyclohexanone,4-hydroxy-4-phenyl;4-hydroxy-4-phenyl-cyclohexanone;

Chemical Property of 4-Hydroxy-4-phenylcyclohexanone

Chemical Property:

• Vapor Pressure: 1.71E-05mmHg at 25°C
• Boiling Point: 349.9oC at 760 mmHg
• Flash Point: 149.1oC
• PSA: 37.30000
• Density: 1.17g/cm3
• LogP: 2.01730

Purity/Quality:

99%, ^*data from raw suppliers

4-Hydroxy-4-phenylcyclohexanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxy-4-phenylcyclohexanone

There total 15 articles about 4-Hydroxy-4-phenylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

cyclohexanedione monoethylene ketal (4746-97-8) + phenylmagnesium bromide (100-58-3) → 4-hydroxy-4-phenylcyclohexanone (51171-73-4)

Guidance literature:

cyclohexanedione monoethylene ketal; phenylmagnesium bromide; In tetrahydrofuran; 2-methyltetrahydrofuran; at 0 - 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 - 20 ℃; for 4h;

DOI:10.1016/j.tetlet.2019.03.037

Reference yield: 85.0%

9-phenyl-3-(1-phenylvinyl)-1,2,5-trioxaspiro[5.5]undec-9-ol → 4-hydroxy-4-phenylcyclohexanone (51171-73-4)

Guidance literature:

With N-benzyl-trimethylammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/ol052378d

Reference yield: 65.0%

4-hydroxy-4-phenyl-cyclohexanone ethylene ketal (94112-58-0) → 4-hydroxy-4-phenylcyclohexanone (51171-73-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 21h;

DOI:10.1002/anie.201507320

upstream raw materials:

phenyllithium

1,4-Cyclohexanedione

4-hydroxy-4-phenyl-cyclohexanone ethylene ketal

3-(1-Phenyl-vinyl)-1,2,5-trioxaspiro[5.5]undec-9-one

Downstream raw materials:

1,4-Dihydroxy-4-phenylcyclohexancarbonitril

1-phenyl-5-hexene-1,4-dione

4-phenyl-3-cyclohexen-1-one

4-cyano-1,1'-biphenyl

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 51171-73-4 4-Hydroxy-4-phenylcyclohexanone

Send

Send

Metric Ton KG G Pound L ML

Send

Send