N-(4-methylpyridin-2-yl)acetamide

Base Information

Chemical Name:N-(4-methylpyridin-2-yl)acetamide
CAS No.:5327-32-2
Molecular Formula:C8H10N2O
Molecular Weight:150.18
Hs Code.:29333990
European Community (EC) Number:803-944-9
NSC Number:3314
DSSTox Substance ID:DTXSID50277644
Nikkaji Number:J454.762D
Wikidata:Q72434642
Mol file:5327-32-2.mol

Synonyms:5327-32-2;N-(4-methylpyridin-2-yl)acetamide;2-acetamido-4-picoline;2-Acetylamino-4-methylpyridine;N-(4-methyl-2-pyridyl)acetamide;2-acetamido-4-methylpyridine;N-(4-methyl-pyridin-2-yl)-acetamide;N-(4-Methyl-pyridine-2-yl)-acetamide;ACETAMIDE, N-(4-METHYL-2-PYRIDINYL)-;NSC3314;4-Picoline, 2-acetamido-;SCHEMBL91475;4-methyl-2-acetylaminopyridine;SCHEMBL13922930;DTXSID50277644;N-(4-Methylpyrdn-2-yl)acetamde;2-(Acetylamino)-4-Methylpyridine;AMY33284;N-(4-methyl-2-pyridinyl)acetamide;NSC 3314;NSC-3314;MFCD00234432;AKOS003865636;AB05238;PS-5449;SB52481;AC-15014;FT-0678106;M2787;F16668;N-(4-Methylpyridin-2-yl)acetamide, AldrichCPR;A829490;AC-907/25004803;J-523071;2-(1-METHYLENE-3-OXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)PROPANOICACID

Suppliers and Price of N-(4-methylpyridin-2-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Acetylamino-4-methylpyridine
5g
$ 55.00

TCI Chemical
N-(4-Methyl-2-pyridyl)acetamide >98.0%(GC)
1g
$ 25.00

TCI Chemical
N-(4-Methyl-2-pyridyl)acetamide >98.0%(GC)
5g
$ 73.00

SynQuest Laboratories
2-Acetylamino-4-methylpyridine 98%
100 g
$ 872.00

SynQuest Laboratories
2-Acetylamino-4-methylpyridine 98%
25 g
$ 287.00

SynQuest Laboratories
2-Acetylamino-4-methylpyridine 98%
5 g
$ 135.00

Sigma-Aldrich
N-(4-Methylpyridin-2-yl)acetamide Aldrich
1g
$ 140.00

Matrix Scientific
N-(4-Methylpyridin-2-yl)acetamide 97%
250mg
$ 136.00

Heterocyclics
N-(4-Methylpyridin-2-yl)acetamide 97%
25g
$ 142.00

Heterocyclics
N-(4-Methylpyridin-2-yl)acetamide 97%
100g
$ 511.00

Total 40 raw suppliers

Chemical Property of N-(4-methylpyridin-2-yl)acetamide

Chemical Property:

Vapor Pressure:7.21E-05mmHg at 25°C
Melting Point:90-94 °C
Refractive Index:1.572
Boiling Point:343.1 °C at 760 mmHg
PKA:13.82±0.70(Predicted)
Flash Point:161.3 °C
PSA：41.99000
Density:1.137 g/cm³
LogP:1.42140
Storage Temp.:Keep Cold
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:150.079312947
Heavy Atom Count:11
Complexity:147

Purity/Quality:

99%, ^*data from raw suppliers

2-Acetylamino-4-methylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22-36-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC=C1)NC(=O)C
Uses 2-Acetylamino-4-methylpyridine is a chemical reagent used in the synthesis of potent inhibitors of Eimeria tenalla cGMP-dependant protein kinase as antiparasitic agents. Also used in the 1-pot synthesis of difluoromethyl-2-pyridone derivatives.

Technology Process of N-(4-methylpyridin-2-yl)acetamide

There total 11 articles about N-(4-methylpyridin-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 695-34-1
2-Amino-4-methylpyridine

: 108-05-4,9003-20-7
vinyl acetate

: 5327-32-2
2-acetylamino-4-methylpyridine

Guidance literature:: With 1,4-diaza-bicyclo[2.2.2]octane; In neat (no solvent); at 70 - 140 ℃; for 0.183333h; Microwave irradiation;
DOI:10.1039/c5nj01436k

Reference yield: 90.0%

: 695-34-1
2-Amino-4-methylpyridine

: 108-24-7
acetic anhydride

: 5327-32-2
2-acetylamino-4-methylpyridine

Guidance literature:: 2-Amino-4-methylpyridine; acetic anhydride; With acetic acid; Reflux;

With ammonium hydroxide; pH=9;

Reference yield: 80.0%

: 461-87-0
2-fluoro-4-methylpyridine

: 124-42-5
acetamidine hydrochloride

: 5327-32-2
2-acetylamino-4-methylpyridine

Guidance literature:: With water; caesium carbonate; In dimethyl sulfoxide; at 90 ℃; for 18h; chemoselective reaction; Schlenk technique;
DOI:10.1039/d0ob01904f