1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one

Base Information

Chemical Name:1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one
CAS No.:56202-01-8
Molecular Formula:C16H16O3
Molecular Weight:256.301
Hs Code.:
DSSTox Substance ID:DTXSID70541273
Wikidata:Q82417594
Mol file:56202-01-8.mol

Synonyms:56202-01-8;1-(2-HYDROXYPHENYL)-3-(4-METHOXYPHENYL)PROPAN-1-ONE;1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-1-Propanone;1-Propanone, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-;SCHEMBL10829648;DTXSID70541273;A18911

Suppliers and Price of 1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one

Chemical Property:

PSA：46.53000
LogP:3.21630
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:256.109944368
Heavy Atom Count:19
Complexity:282

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CCC(=O)C2=CC=CC=C2O

Technology Process of 1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one

There total 12 articles about 1-(2-Hydroxyphenyl)-3-(4-methoxyphenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 34000-29-8
[E]-3-(p-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one

: 56202-01-8
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-propan-1-one

Guidance literature:: With ammonium formate; palladium on activated charcoal; In tetrahydrofuran; methanol; at 20 ℃; for 0.6h;

Reference yield: 92.0%

: 3327-24-0
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

: 56202-01-8
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-propan-1-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In dichloromethane; at 20 ℃; for 6h; under 760.051 Torr;
DOI:10.1002/adsc.202000892

Reference yield: 88.0%

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 123-11-5
4-methoxy-benzaldehyde

: 56202-01-8
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-propan-1-one

Guidance literature:: o-hydroxyacetophenone; 4-methoxy-benzaldehyde; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃;

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmcl.2020.127674