34000-29-8

Basic information

• Product Name: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-
• Synonyms: [E]-3-(p-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one;1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one;(2E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one;(E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one;(E)-3-(4-methoxyphenyl)-1-(2-hydroxyphenyl)-2-propen-1-one
• CAS NO: 34000-29-8
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Mol File: 34000-29-8.mol
• Article Data: 86

Chemical Properties

• Melting Point: 81-83 °C
• Boiling Point: 444.8±45.0 °C(Predicted)
• Density: 1?+-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-(34000-29-8)
• EPA Substance Registry System: 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-(34000-29-8)

Safety Data

• Hazardous Substances Data: 34000-29-8(Hazardous Substances Data)

Upstream product

• 39729-17-4 2'-hydroxy-4-methoxychalcone dibromide 
• 67-56-1 methanol 
• 62536-68-9 2'-acetoxy-4-methoxy-trans-chalcone 
• 65009-00-9 O-phenyl N,N-diethylcarbamate 
• 123-11-5 4-methoxy-benzaldehyde 
• 19311-91-2 N,N-diethylsalicylamide 
• 35095-60-4 2'-Methoxymethoxy-4-methoxy-chalcon 
• 637-69-4 4-Methoxystyrene 
• 90-02-8 salicylaldehyde 
• 122-79-2 Phenyl acetate 
• 19115-30-1 1-(4-methoxyphenyl)-2-propyn-1-ol 
• 32865-61-5 2-iodophenyl acetate 
• 261785-29-9 3-(o-acetoxyphenyl)-1-(p-methoxyphenyl)prop-2-yn-ol 
• 74-88-4 methyl iodide 

Downstream Products

• 62536-69-0 2'-acetoxy-4'-methoxychalcone 
• 1621-57-4 2,3-dihydro-3-hydroxy-7-methoxyflavone 
• 80140-49-4 6-p-Methoxyphenyl-6H-<1>benzopyrano<4,3-b><1,8>naphthyridine 
• 148404-08-4 1-formyl-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-2-pyrazoline 
• 36685-41-3 (Z)-4'-methoxyaurone 
• 4143-74-2 4'-methoxyflavone 
• 3034-08-0 2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one 
• 39729-17-4 2'-hydroxy-4-methoxychalcone dibromide 
• 56202-01-8 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-propan-1-one 
• 6515-31-7 3-hydroxy-2-(4-methoxy-phenyl)-chroman-4-one 
• 129878-46-2 (E)-2'-hydroxy-4-methoxychalcone epoxide 
• 5162-64-1 (+/-)-cis-4'-methoxyflavan-4-ol 
• 90834-23-4 4-[(E)-2-(4-Methoxy-phenyl)-vinyl]-chromen-2-one 
• 75780-71-1 3',5'-dibromo-2'-hydroxy-4-methoxy-trans-chalcone 

Relevant articles and documents

Synthesis, characterization and biological activities of some Ru(II) complexes with substituted chalcones and their applications as chemotherapeutics against breast cancer

Four new Ru(II) DMSO complexes with substituted chalcone ligands viz. (E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one (HL1), (E)-1-(2-hydroxyphenyl)-3-(4-nitrophenyl)prop-2-en-1-one (HL2), (E)-3-(4-(dimethylamino)phenyl)-1-(2-hydroxyphenyl)prop

Convenient synthesis of flavanone derivatives via oxa-Michael addition using catalytic amount of aqueous cesium fluoride

A total of 36 flavanones, which included polycyclic aromatic and heterocyclic rings, were readily synthesized via oxa-Michael addition from the corresponding hydroxychalcones with a catalytic amount of aqueous cesium fluoride solution under mild conditions. This method could be applied to the scalable synthesis of eriodictyol as a known potent inhibitor of the SARS-CoV-2 spike protein.

Crystal-packing modes determine the solid-state ESIPT fluorescence in highly dipolar 2′-hydroxychalcones

This work describes the systematic study of the structure-luminescence relationship of 15 hydroxy-chalcones directly in the crystal state. Chalcones are easily assembled at the gram scale allowing for efficient variation of their substitution motifs. Our molecule variants combine two modes of fluorescence generation, ESIPT and ICT, both known for their potential to achieve significant quantum yields even with emission in the red to near infrared, a region preferred for technologies as diverse as optoelectronics and chemical sensing. Quantum yields as high as 48% (at 665 nm) and emission wavelengths in the deep red region (710 nm, 5%) were achieved with variants equipped with a strained amino substituent in the donor portion (azetidinyl). Systematic XRD analysis of large monocrystals allowed for the identification of the subtle interplay of several inter- and intra-molecular parameters in achieving such performances, be it intramolecular planarity, non-classical H-bonds, and stacking modes.