4,4'-Difluorostilbene

Base Information

• Chemical Name: 4,4'-Difluorostilbene
• CAS No.: 588-56-7
• Molecular Formula: C14H10F2
• Molecular Weight: 216.23
• DSSTox Substance ID: DTXSID601269825
• Mol file: 588-56-7.mol

Synonyms:4,4'-difluorostilbene;588-56-7;DTXSID601269825;1,1'-(1,2-Ethenediyl)bis[4-fluorobenzene]

Chemical Property of 4,4'-Difluorostilbene

Chemical Property:

• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 216.07505664
• Heavy Atom Count: 16
• Complexity: 197

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C=CC2=CC=C(C=C2)F)F

Technology Process of 4,4'-Difluorostilbene

There total 54 articles about 4,4'-Difluorostilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-1,2-di(4-fluorophenyl)ethene (588-56-7,40286-61-1,146565-92-6,146565-94-8,27764-15-4) → (Z)-1,2-bis(4-fluorophenyl)ethylene (588-56-7,27764-15-4,146565-92-6,146565-94-8,40286-61-1)

Guidance literature:

With 8,9-bis((R)-2-(isobutyryloxy)propyl)-7,10-dimethoxyperyleno-[1,12-def][1,3]dioxepine-5,6,11,12-tetrayl tetrakis(2-methylpropanoate); In toluene; at 20 ℃; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1021/acs.joc.1c01876

Reference yield: 90.0%

1,2-bis(4-fluorophenyl)acetylene (5216-31-9) → (E)-1,2-di(4-fluorophenyl)ethene (588-56-7,40286-61-1,146565-92-6,146565-94-8,27764-15-4)

Guidance literature:

With alpha-D-glucopyranose; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; In 1,2-dichloro-ethane; at 120 ℃; for 24h; stereoselective reaction;

DOI:10.1002/cssc.201801770

Reference yield: 90.0%

carbon monoxide (201230-82-2) + 1,2-bis(4-fluorophenyl)acetylene (5216-31-9) → (Z)-1,2-bis(4-fluorophenyl)ethylene (588-56-7,27764-15-4,146565-92-6,146565-94-8,40286-61-1) + (E)-2,3-bis(4-fluorophenyl)acrylaldehyde

Guidance literature:

With acetylacetonatodicarbonylrhodium(l); C₂₁H₁₀F₁₂NOP; hydrogen; In toluene; at 55 ℃; for 20h; under 3750.38 Torr; stereoselective reaction;

DOI:10.1039/c3sc50725d

upstream raw materials:

allylbenzene

para-fluorostyrene

(4-fluorobenzyl)(triphenyl)phosphonium bromide

(E)-1,2-di(4-fluorophenyl)ethene

Downstream raw materials:

4,4'-difluorobibenzyl

(2R,3S)-2,3-bis(4-fluorophenyl)oxirane

(Z)-1,2-bis(4-fluorophenyl)ethylene

2,3-bis(4-fluorophenyl)propanenitrile