N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester

Base Information

Chemical Name:N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester
CAS No.:59490-36-7
Molecular Formula:C18H19NO4
Molecular Weight:313.353
Hs Code.:
DSSTox Substance ID:DTXSID601234953

Synonyms:N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester;SCHEMBL25496384;DTXSID601234953;59490-36-7

Suppliers and Price of N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:313.13140809
Heavy Atom Count:23
Complexity:385

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)NC(CC2=CC=CC=C2)C(=O)OC
Isomeric SMILES:COC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OC

Technology Process of N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester

There total 10 articles about N-(4-Methoxybenzoyl)-L-phenylalanine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 100-07-2
4-methoxy-benzoyl chloride

: 59490-36-7
(2S)-methyl 2--3-phenyl-1-propanoate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b04129

Reference yield: 98.0%

: 67-56-1
methanol

: 217446-35-0
4-benzyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole

: 59490-36-7
(2S)-methyl 2--3-phenyl-1-propanoate

Guidance literature:: With (S)-2-(2-((2,6-diisopropylphenyl)carbamoyl)pyrrolidin-1-yl)-4-(pyrrolidin-1-yl)pyridine 1-oxide; benzoic acid; In dichloromethane; at 20 ℃; for 24h; Reagent/catalyst; Solvent; enantioselective reaction; Catalytic behavior; Kinetics; Resolution of racemate;
DOI:10.1021/jacs.0c09075

Reference yield:

: 59490-27-6
methyl (Z)-2-(4-methoxybenzamido)-3-phenylacrylate

: 59490-36-7
(2S)-methyl 2--3-phenyl-1-propanoate

: methyl (4-methoxybenzoyl)-R-phenylalaninate

Guidance literature:: With hydrogen; nickel(II) acetate tetrahydrate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); In 2,2,2-trifluoroethanol; at 50 ℃; for 36h; under 22801.5 Torr; enantioselective reaction; Autoclave;
DOI:10.1002/anie.201916534