Cycloheptanecarboxylic acid methyl ester

Base Information

• Chemical Name: Cycloheptanecarboxylic acid methyl ester
• CAS No.: 60433-00-3
• Molecular Formula: C9H16O2
• Molecular Weight: 156.225
• Hs Code.: 2916209090
• Mol file: 60433-00-3.mol

Synonyms:Cycloheptanecarboxylic acid,methyl ester;Cycloheptanecarboxylic acid, methyl ester;methyl cycloheptanoate;Cycloheptan-carbonsaeure-methylester;

Chemical Property of Cycloheptanecarboxylic acid methyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 2.12980
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

methylcycloheptanecarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cycloheptanecarboxylic acid methyl ester

There total 14 articles about Cycloheptanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

methanol (67-56-1) + cycloheptanoic acid (1460-16-8) → methyl cycloheptanecarboxylate (60433-00-3)

Guidance literature:

With sulfuric acid; In neat liquid; at 60 ℃; for 2.5h;

DOI:10.1021/jacs.1c05206

Reference yield: 81.0%

methanol (67-56-1) + carbon monoxide (201230-82-2) + cycloheptanol (502-41-0) → methyl cycloheptanecarboxylate (60433-00-3)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; trifluorormethanesulfonic acid; α,α′-bis(2-pyridyl(tert-butyl)phosphino)-o-xylene; at 140 ℃; for 48h; under 30003 Torr; Autoclave; Inert atmosphere;

DOI:10.1002/anie.201701950

Reference yield: 76.0%

methanol (67-56-1) + carbon dioxide (124-38-9,18923-20-1) + Cycloheptene (628-92-2,45509-99-7) → methyl cycloheptanecarboxylate (60433-00-3)

Guidance literature:

With dicobalt octacarbonyl; α-{Ru2Cl4(CO)6}; 1-butyl-3-methylimidazolium chloride; at 160 ℃; for 20h; under 30003 Torr; Autoclave; Inert atmosphere; Ionic liquid;

DOI:10.1039/c8gc02289e

upstream raw materials:

methanol

cycloheptanoic acid

diazomethane

2-chlorocyclooctanone

Downstream raw materials:

Cycloheptyl-diphenyl-carbinol

Cycloheptyliden-bis-(4-methoxy-phenyl)-methan

1-isopropylcycloheptyl 4-fluorophenyl ketone

(4-fluoro-phenyl)-(1-isopropyl-cycloheptyl)-methanol