N-(3-chlorophenyl)picolinamide

Base Information

Chemical Name:N-(3-chlorophenyl)picolinamide
CAS No.:61350-00-3
Molecular Formula:C12H9ClN2O
Molecular Weight:232.669
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00356877
Nikkaji Number:J3.290.936A
Wikidata:Q27089187
Pharos Ligand ID:3PDBNYXZCPGJ
ChEMBL ID:CHEMBL556667
Mol file:61350-00-3.mol

Synonyms:N-(3-chlorophenyl)picolinamide;VU0364770

Suppliers and Price of N-(3-chlorophenyl)picolinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
VU 0364770
10mg
$ 423.00

TRC
N-(3-Chlorophenyl)-2-pyridinecarboxamide
100mg
$ 625.00

Tocris
VU0364770 ≥99%(HPLC)
10
$ 173.00

Tocris
VU0364770 ≥99%(HPLC)
50
$ 724.00

Matrix Scientific
N-(3-Chlorophenyl)picolinamide 95%
25g
$ 2220.00

Matrix Scientific
N-(3-Chlorophenyl)picolinamide 95%
5g
$ 648.00

DC Chemicals
VU0364770 >98%
100 mg
$ 300.00

DC Chemicals
VU0364770 >98%
250 mg
$ 500.00

DC Chemicals
VU0364770 >98%
1 g
$ 1100.00

ChemScene
VU0364770 99.57%
100mg
$ 320.00

Total 21 raw suppliers

Chemical Property of N-(3-chlorophenyl)picolinamide

Chemical Property:

Melting Point:81-83 °C
Boiling Point:293.6±20.0 °C(Predicted)
PKA:11.24±0.70(Predicted)
PSA：45.48000
Density:1.341±0.06 g/cm3(Predicted)
LogP:3.37130
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:232.0403406
Heavy Atom Count:16
Complexity:247

Purity/Quality:

99%, ^*data from raw suppliers

VU 0364770 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
Uses N-(3-Chlorophenyl)-2-pyridinecarboxamide shows positive allosteric modulation at the mGlu4 receptors in combination with other antagonists resulting in treatment for the neurodegenerative Parkinson’s disease. N-(3-Chlorophenyl)-2-pyridinecarboxamide shows positive allosteric modulation at the mGlu4 receptors in combination with other antagonists resulting in treatment for the neurodegenerative Parkinson’s disease (1).

Technology Process of N-(3-chlorophenyl)picolinamide

There total 5 articles about N-(3-chlorophenyl)picolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 98-98-6
2-Picolinic acid

: 108-42-9
3-chloro-aniline

: 61350-00-3
V⁽⁶⁴⁷⁾U₀₃₇₀

Guidance literature:: 2-Picolinic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 20 ℃;

3-chloro-aniline; In 1,4-dioxane; at 50 ℃;
DOI:10.1021/jm9005065