2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

Base Information

Chemical Name:2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole
CAS No.:61363-17-5
Molecular Formula:C18H17NO
Molecular Weight:263.339
Hs Code.:
DSSTox Substance ID:DTXSID90697145
Nikkaji Number:J2.395.699C
Wikidata:Q82626966

Synonyms:2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole;61363-17-5;2-(4-METHOXYPHENYL)-5-METHYL-1-PHENYLPYRROLE;DTXSID90697145;1-Phenyl-2-(4-methoxyphenyl)-5-methyl-1H-pyrrole

Suppliers and Price of 2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:263.131014166
Heavy Atom Count:20
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(N1C2=CC=CC=C2)C3=CC=C(C=C3)OC

Technology Process of 2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

There total 4 articles about 2-(4-Methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 201230-82-2
carbon monoxide

: 5720-07-0
4-methoxyphenylboronic acid

: 78-94-4,25038-87-3
methyl vinyl ketone

: 62-53-3
aniline

: 61363-17-5
2-(4-methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

Guidance literature:: carbon monoxide; 4-methoxyphenylboronic acid; methyl vinyl ketone; carbonylhydridetris(triphenylphosphine)rhodium(I); In methanol; at 80 ℃; for 18h; under 15001.2 Torr;

aniline; With iodine; In tetrahydrofuran; at 40 ℃;
DOI:10.1016/j.tet.2006.09.035

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 61363-17-5
2-(4-methoxyphenyl)-5-methyl-1-phenyl-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / ethanol / 75 °C

2: aq. phosphate buffer; acetonitrile / 23 °C / pH 7.2

With triethylamine; In aq. phosphate buffer; ethanol; acetonitrile; 1: |Stetter 1,4-Dicarbonyl Synthesis / 2: |Paal-Knorr Pyrrole Synthesis;
DOI:10.1039/d0ra06962k