2-Bromo-1-methoxynaphthalene

Base Information

• Chemical Name: 2-Bromo-1-methoxynaphthalene
• CAS No.: 62012-54-8
• Molecular Formula: C11H9BrO
• Molecular Weight: 237.096
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID50504361
• Nikkaji Number: J1.415.100A
• Wikidata: Q82358808
• Mol file: 62012-54-8.mol

Synonyms:2-Bromo-1-methoxynaphthalene;62012-54-8;2-bromo-1-methoxy-naphthalene;SCHEMBL8200761;DTXSID50504361;WLZ2922;UOVMWQHKZYGAGR-UHFFFAOYSA-N;MFCD17012354;AKOS015919648;TS-00678;CS-0041682;FT-0736670;F21158;A833531

Chemical Property of 2-Bromo-1-methoxynaphthalene

Chemical Property:

• Boiling Point: 161 °C(Press: 14 Torr)
• PSA: 9.23000
• Density: 1.447±0.06 g/cm3(Predicted)
• LogP: 3.61090
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 235.98368
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-methoxynaphthalene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC2=CC=CC=C21)Br

Technology Process of 2-Bromo-1-methoxynaphthalene

There total 6 articles about 2-Bromo-1-methoxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-Methoxynaphthalene (2216-69-5) → 1-bromo-4-methoxynaphthalene (5467-58-3) + 2-bromo-1-methoxynaphthalene (62012-54-8)

Guidance literature:

With Oxone; potassium bromide; In methanol; at 20 ℃; for 4h;

DOI:10.1081/SCC-120006001

Reference yield: 85.6%

2-bromo-1-naphthol (771-15-3) + methyl iodide (74-88-4) → 2-bromo-1-methoxynaphthalene (62012-54-8)

Guidance literature:

With potassium hydroxide; In acetonitrile; at 40 ℃; for 12h;

DOI:10.1016/j.bmc.2019.07.031

Reference yield:

α-naphthol (90-15-3) → 2-bromo-1-methoxynaphthalene (62012-54-8)

Guidance literature:

Multi-step reaction with 2 steps

1: CCl₄; bromine

2: ethanol; diethyl ether

With tetrachloromethane; diethyl ether; ethanol; bromine;

upstream raw materials:

diazomethane

2-bromo-1-naphthol

methyl iodide

bromine