1-Dimethylamino-4-trimethylsilylbenzene

Base Information

• Chemical Name: 1-Dimethylamino-4-trimethylsilylbenzene
• CAS No.: 16087-24-4
• Molecular Formula: C11H19 N Si
• Molecular Weight: 193.364
• Hs Code.: 2931900090
• Mol file: 16087-24-4.mol

Synonyms:Aniline,N,N-dimethyl-p-(trimethylsilyl)- (6CI,7CI,8CI);N,N-Dimethyl-p-(trimethylsilyl)aniline; [4-(N,N-Dimethylamino)phenyl]trimethylsilane;p-(Trimethylsilyl)-N,N-dimethylaniline; p-Dimethylaminophenyltrimethylsilane

Chemical Property of 1-Dimethylamino-4-trimethylsilylbenzene

Chemical Property:

• Vapor Pressure: 0.018mmHg at 25°C
• Melting Point: 27-28 °C
• Boiling Point: 253.7°Cat760mmHg
• PKA: 4.57±0.12(Predicted)
• Flash Point: 107.2°C
• PSA: 3.24000
• Density: 0.9g/cm³
• LogP: 2.29780

Purity/Quality:

98% ^*data from raw suppliers

N,N-DIMETHYL-4-(TRIMETHYLSILYL)ANILINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 1-Dimethylamino-4-trimethylsilylbenzene

There total 10 articles about 1-Dimethylamino-4-trimethylsilylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

chloro-trimethyl-silane (75-77-4) + 4-bromo-N,N-dimethylaniline (586-77-6) → N,N-dimethyl-4-(trimethylsilyl)aniline (16087-24-4)

Guidance literature:

4-bromo-N,N-dimethylaniline; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1h;

chloro-trimethyl-silane; In diethyl ether; hexane; at -78 - 20 ℃; for 4h;

DOI:10.1002/asia.201000522

Reference yield: 81.0%

1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + vinyltriethylsilane (1112-54-5) + 4-cyano-N,N-dimethylaniline (1197-19-9) → (E)-dimethyl[4-(2-triethylsilanylvinyl)phenyl]amine (866364-01-4) + N,N-dimethyl-4-(trimethylsilyl)aniline (16087-24-4)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; P(p-C₆H₄F)3; In ethyl-cyclohexane; at 130 ℃; for 30h; Inert atmosphere;

DOI:10.1021/ol100481h

Reference yield: 76.0%

chloro-trimethyl-silane (75-77-4) + 4-dimethylaminophenyllithium (13190-50-6) → N,N-dimethyl-4-(trimethylsilyl)aniline (16087-24-4)

Guidance literature:

In not given; (CH3)3SiCl and LiC6H4N(CH3)2; hydrolysis;;

DOI:10.1021/ja01156a104 DOI:10.1021/ja01106a043 DOI:10.1021/ja01114a041 DOI:10.1021/ja01174a049

upstream raw materials:

chloro-trimethyl-silane

4-dimethylaminophenyllithium

4-bromo-N,N-dimethylaniline

1,1,1,2,2,2-hexamethyldisilane

Downstream raw materials:

trimethyl-(4-trimethylsilanyl-phenyl)-ammonium; iodide

N,N-dimethyl-aniline

Triphenylsilyl chloride

tricarbonyl[5-(4-dimethylaminophenyl)cyclohexa-1,3-diene]iron