Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid, 3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester, (1R,2R,3R,5R,6R)-

Base Information

Chemical Name:Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid, 3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester, (1R,2R,3R,5R,6R)-
CAS No.:820244-80-2
Molecular Formula:C20H18Cl2FNO7
Molecular Weight:474.27
Hs Code.:

Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid,
3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester,
(1R,2R,3R,5R,6R)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid, 3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester, (1R,2R,3R,5R,6R)-

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MSDS Files:: SDS file from LookChem

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Technology Process of Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid, 3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester, (1R,2R,3R,5R,6R)-

There total 1 articles about Spiro[bicyclo[3.1.0]hexane-2,4'-oxazolidine]-3',6-dicarboxylic acid, 3-[(3,4-dichlorophenyl)methoxy]-6-fluoro-5'-oxo-, 3'-(2-propenyl) ester, (1R,2R,3R,5R,6R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 820244-79-9
(1R,2R,3R,5R,6R)-2-allyloxycarbonylamino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 820244-80-2
(1'R,2'R,3'R,5'R,6'R)-3'-(3,4-dichlorobenzyloxy)-6'-fluoro-3-allyloxycarbonyl-5-oxooxazinone-4-spiro-2'-bicyclo[3.1.0]hexane-6'-carboxylic acid

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 6h; Heating;
DOI:10.1016/j.bmc.2006.01.060

Reference yield: 48.0%

: 820244-80-2
(1'R,2'R,3'R,5'R,6'R)-3'-(3,4-dichlorobenzyloxy)-6'-fluoro-3-allyloxycarbonyl-5-oxooxazinone-4-spiro-2'-bicyclo[3.1.0]hexane-6'-carboxylic acid

: 1470-94-6
5-hydroxy-2,3-dihydro-1H-indene

: 1431218-28-8
C₂₉H₂₆Cl₂FNO₇

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 18h;