N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide

Base Information

Chemical Name:N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide
CAS No.:88769-08-8
Molecular Formula:C₁₄H₂₃NO₂Si
Molecular Weight:265.428
Hs Code.:
DSSTox Substance ID:DTXSID10523356
Wikidata:Q82389391

Synonyms:88769-08-8;N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide;N,N-Diethyl-2-[(trimethylsilyl)oxy]benzamide;DTXSID10523356

Suppliers and Price of N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:265.149805511
Heavy Atom Count:18
Complexity:272

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=CC=CC=C1O[Si](C)(C)C

Technology Process of N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide

There total 2 articles about N,N-Diethyl-2-((trimethylsilyl)oxy)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51674-10-3
N,N-diethyl-2-methoxybenzamide

: 88769-08-8
N,N-Diethyl-2-trimethylsilanyloxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: BBr₃ / CH₂Cl₂ / -78 °C

2: 6 h / 40 °C

With boron tribromide; In dichloromethane;
DOI:10.1016/S0040-4039(00)85942-0

Reference yield:

: 19311-91-2
N,N-diethylsalicylamide

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 88769-08-8
N,N-Diethyl-2-trimethylsilanyloxy-benzamide

Guidance literature:: at 40 ℃; for 6h;
DOI:10.1016/S0040-4039(00)85942-0

Reference yield: 68.0%

: 88769-08-8
N,N-Diethyl-2-trimethylsilanyloxy-benzamide

: o-hydroxyvalerophenone

: 88769-09-9
N,N-Diethyl-2-hydroxy-6-trimethylsilanyl-benzamide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 - 25 ℃; Mechanism; 3-deuterated derivative was investigated;
DOI:10.1016/S0040-4039(00)85942-0