Technology Process of Phenol, 4-methoxy-2-methyl-5-(1-methylethyl)-
There total 8 articles about Phenol, 4-methoxy-2-methyl-5-(1-methylethyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide;
In
methanol; N,N-dimethyl-formamide;
at 110 ℃;
for 48h;
DOI:10.1080/00304949609356526
- Guidance literature:
-
thymohydroquinone;
With
sodium hydroxide;
In
methanol;
at 20 ℃;
for 0.25h;
Inert atmosphere;
Alkaline conditions;
methyl iodide;
In
methanol;
at 65 ℃;
for 1h;
Reagent/catalyst;
Overall yield = 90 percent; Overall yield = 87.3 mg;
Cooling;
Inert atmosphere;
DOI:10.1021/acs.jnatprod.9b00339
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 78 percent / Br2 / acetic acid / Ambient temperature
2: 80 percent / Br2 / acetic acid / 3 h / Ambient temperature
3: 82 percent / CuI / methanol; dimethylformamide / 48 h / 110 °C
With
copper(l) iodide; bromine;
In
methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1080/00304949609356526
