tert-Butyl (3-ethylpyridin-2-yl)carbamate

Base Information

Chemical Name:tert-Butyl (3-ethylpyridin-2-yl)carbamate
CAS No.:149489-03-2
Molecular Formula:C12H18N2O2
Molecular Weight:222.286
Hs Code.:2933399090
DSSTox Substance ID:DTXSID30455842
Wikidata:Q72477076
Mol file:149489-03-2.mol

Synonyms:149489-03-2;tert-Butyl (3-ethylpyridin-2-yl)carbamate;Tert-butyl N-(3-ethylpyridin-2-yl)carbamate;(3-Ethyl-pyridin-2-yl)-carbamic acid tert-butyl ester;Tert-butyl 3-ethylpyridin-2-ylcarbamate;2-t-Butoxycarbonylamino-3-ethylpyridine;Carbamic acid, N-(3-ethyl-2-pyridinyl)-, 1,1-dimethylethyl ester;Carbamic acid, (3-ethyl-2-pyridinyl)-, 1,1-dimethylethyl ester;tert-Butyl(3-ethylpyridin-2-yl)carbamate;SCHEMBL69347;N-Boc-3-Ethylpyridin-2-Amine;DTXSID30455842;IQRKFAYMMZQJCK-UHFFFAOYSA-N;N-(3-ETHYL-2-PYRIDINYL)CARBAMIC ACID TERT-BUTYL ESTER;ZFA48903;AKOS016007002;SB33772;TS-00530;CS-0136784;FT-0753842;D87986;EN300-219458;A848154;Carbamic acid,(3-ethyl-2-pyridinyl)-,1,1-dimethylethyl ester (9Cl);tert-butyl 3-ethylpyridin-2-ylcarbamate

Suppliers and Price of tert-Butyl (3-ethylpyridin-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3-Ethyl-pyridin-2-yl)-carbamicacidtert-butylester
250mg
$ 330.00

Matrix Scientific
tert-Butyl 3-ethylpyridin-2-ylcarbamate 97%
1g
$ 617.00

Labseeker
2-t-Butoxycarbonylamino-3-ethylpyridine 95
5g
$ 1217.00

J&W Pharmlab
(3-Ethyl-pyridin-2-yl)-carbamicacidtert-butylester 96%
5g
$ 1995.00

J&W Pharmlab
(3-Ethyl-pyridin-2-yl)-carbamicacidtert-butylester 96%
500mg
$ 249.00

J&W Pharmlab
(3-Ethyl-pyridin-2-yl)-carbamicacidtert-butylester 96%
1g
$ 499.00

Crysdot
tert-Butyl(3-ethylpyridin-2-yl)carbamate 95+%
1g
$ 377.00

Chemenu
tert-butyl(3-ethylpyridin-2-yl)carbamate 95%
1g
$ 356.00

Atlantic Research Chemicals
tert-Butyl3-Ethylpyridin-2-ylcarbamate 95%
1gm:
$ 236.82

American Custom Chemicals Corporation
TERT-BUTYL-(3-ETHYLPYRIDIN-2-YL)CARBAMATE 95.00%
5MG
$ 502.80

Total 21 raw suppliers

Chemical Property of tert-Butyl (3-ethylpyridin-2-yl)carbamate

Chemical Property:

Appearance/Colour:White to off-white powder
PSA：51.22000
Density:1.087
LogP:3.06400
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:222.136827821
Heavy Atom Count:16
Complexity:236

Purity/Quality:

98+% ^*data from raw suppliers

(3-Ethyl-pyridin-2-yl)-carbamicacidtert-butylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(N=CC=C1)NC(=O)OC(C)(C)C

Technology Process of tert-Butyl (3-ethylpyridin-2-yl)carbamate

There total 5 articles about tert-Butyl (3-ethylpyridin-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 138343-75-6
tert-butyl (3-methylpyridin-2-yl)carbamate

: 74-88-4
methyl iodide

: 149489-03-2
tert-butyl (3-ethylpyridin-2-yl)carbamate

Guidance literature:: tert-butyl (3-methylpyridin-2-yl)carbamate; With n-butyllithium; In tetrahydrofuran; at -40 - 0 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -78 - -60 ℃; for 0.5h;

Reference yield:

: 109-72-8,29786-93-4
n-butyllithium

: 38427-94-0
N-(tert-butoxycarbonyl)-2-aminopyridine

: 75-03-6
ethyl iodide

: 149489-03-2
tert-butyl (3-ethylpyridin-2-yl)carbamate

Guidance literature:: In tetrahydrofuran;

Reference yield:

: 1603-40-3
3-methylpyridin-2-ylamine

: 149489-03-2
tert-butyl (3-ethylpyridin-2-yl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / ethyl acetate; hexane / 0.83 h / 58 °C

2: 1.) n-BuLi / 1.) THF, 0 - 3 deg C, 1 h, 2.) THF, -75 deg C, 1 h

With n-butyllithium; In hexane; ethyl acetate;
DOI:10.1055/s-1996-4312