1-Benzyl-2-naphthol

Base Information

• Chemical Name: 1-Benzyl-2-naphthol
• CAS No.: 36441-31-3
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• Hs Code.: 2907199090
• NSC Number: 143573
• DSSTox Substance ID: DTXSID10301459
• Nikkaji Number: J89.113D
• Wikidata: Q82045407
• ChEMBL ID: CHEMBL122078
• Mol file: 36441-31-3.mol

Synonyms:1-benzyl-2-naphthol;36441-31-3;CHEMBL122078;1-benzylnaphthalen-2-ol;NSC143573;1-Benzyl-naphthalen-2-ol;SCHEMBL6405225;DTXSID10301459;BDBM50012680;NSC-143573

Chemical Property of 1-Benzyl-2-naphthol

Chemical Property:

• Vapor Pressure: 2.9E-07mmHg at 25°C
• Melting Point: 114°C
• Refractive Index: 1.5000 (estimate)
• Boiling Point: 408.7°Cat760mmHg
• Flash Point: 196.3°C
• PSA: 20.23000
• Density: 1.163g/cm³
• LogP: 4.13620
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 234.104465066
• Heavy Atom Count: 18
• Complexity: 256

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC2=C(C=CC3=CC=CC=C32)O

Technology Process of 1-Benzyl-2-naphthol

There total 47 articles about 1-Benzyl-2-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.9%

1-(phenyl(morpholin-4-yl)methyl)naphthalen-2-ol (24685-08-3) → 1-benzyl-2-naphthol (36441-31-3)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; for 1h; Heating;

DOI:10.1080/00397910601163547

Reference yield: 90.0%

benzyl bromide (100-39-0) + β-naphthol (135-19-3) → 1-benzyl-2-naphthol (36441-31-3)

Guidance literature:

With lithium hydroxide; at 85 ℃; for 2h;

DOI:10.1016/S0040-4039(01)91111-6

Reference yield: 82.0%

1-[phenyl(piperidin-1-yl)methyl]naphthalen-2-ol (6278-04-2,500352-92-1,521960-31-6) → 1-benzyl-2-naphthol (36441-31-3)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; for 2h; Heating;

DOI:10.1080/00397910601163547

upstream raw materials:

methanol

benzylidene-1,1'-bis(2-naphthol)

sodium methylate

2-benzyloxynaphthalene

Refernces

• 1、 Badri, Meryam. "Ionic liquids as solvents for the regioselective O-alkylation of C/O ambident nucleophiles". . p. 4435 - 4438. Retrieved 1992.
• 2、 Jazzaa, Abdulaziz Al,Clark, James H.,Miller, Jack M.. "THE ROLE HYDROGEN BONDING IN THE AUTOOXIDATION AND ALKYLATION OF 2-NAPHTHOLS". . p. 89 - 92. Retrieved 1983.
• 3、 -. "6-HYDROXY-2-NAPHTHALENYL FLUORENE DERIVATIVES AND LENS AND CAMERA MODULE USING THE SAME". Paragraph 0081-0083. . Retrieved 2016/02/16.
• 4、 Balint, Erika,Kovacs, Orsolya,Drahos, Laszlo,Keglevich, Gyoergy. "Microwave-Assisted solid-liquid phase alkylation of naphthols". . p. 330 - 336. Retrieved 2013/07/26.