2-Isopropoxy-3-methoxybenzaldehyde

Base Information

• Chemical Name: 2-Isopropoxy-3-methoxybenzaldehyde
• CAS No.: 75792-35-7
• Molecular Formula: C11H14 O3
• Molecular Weight: 194.23
• DSSTox Substance ID: DTXSID40392754
• Nikkaji Number: J1.907.415C
• Wikidata: Q82191144
• Mol file: 75792-35-7.mol

Synonyms:2-isopropoxy-3-methoxybenzaldehyde;75792-35-7;3-methoxy-2-(propan-2-yloxy)benzaldehyde;3-methoxy-2-propan-2-yloxybenzaldehyde;SCHEMBL1253814;DTXSID40392754;STK438716;AKOS001116177;CS-0221339;EN300-08911;2-Hydroxy-3-methoxybenzaldehyde, isopropyl ether;Z55928984

Chemical Property of 2-Isopropoxy-3-methoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0.00195mmHg at 25°C
• Boiling Point: 291.5°C at 760 mmHg
• Flash Point: 120.9°C
• Density: 1.064g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 179

Purity/Quality:

98%Min ^*data from raw suppliers

2-ISOPROPOXY-3-METHOXYBENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1=C(C=CC=C1OC)C=O

Technology Process of 2-Isopropoxy-3-methoxybenzaldehyde

There total 5 articles about 2-Isopropoxy-3-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-methoxy-2-hydroxybenzaldehyde (148-53-8) + isopropyl bromide (75-26-3) → 2-isopropoxy-3-methoxy-benzaldehyde (75792-35-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 110 ℃; Industry scale; Inert atmosphere;

Reference yield: 100.0%

→ 2-isopropoxy-3-methoxy-benzaldehyde (75792-35-7)

Guidance literature:

Reference yield: 96.0%

2-iodo-propane (75-30-9) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → 2-isopropoxy-3-methoxy-benzaldehyde (75792-35-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 20h;

DOI:10.1021/acs.jmedchem.9b00551

upstream raw materials:

2-iodo-propane

3-methoxy-2-hydroxybenzaldehyde

isopropyl bromide

tert-butyl methyl ether

Downstream raw materials:

(2-isopropopoxy-3-methoxyphenyl)methanol

2-isopropoxy-1-methoxy-3-(2-nitro-but-1-enyl)-benzene

(2-isopropoxy-3-methoxyphenyl)acetylene