1,1-Diphenyl-1,2-propanediol

Base Information

• Chemical Name: 1,1-Diphenyl-1,2-propanediol
• CAS No.: 52183-00-3
• Molecular Formula: C15H16O2
• Molecular Weight: 228.291
• European Community (EC) Number: 637-116-1
• DSSTox Substance ID: DTXSID50966546
• Nikkaji Number: J781.810F
• Mol file: 52183-00-3.mol

Synonyms:1,1-diphenylpropane-1,2-diol;1,1-Diphenyl-1,2-propanediol;52183-00-3;BRN 1964828;1,2-Propanediol, 1,1-diphenyl-;(R)-1,1-Diphenyl-1,2-propanediol;Dioxy-Diphenyl-Propan;CBDivE_002257;SCHEMBL301345;DTXSID50966546;HMS1577M02;STL495409;AKOS004903746;LS-120378;FT-0639861;AE-562/43461494

Chemical Property of 1,1-Diphenyl-1,2-propanediol

Chemical Property:

• Boiling Point: 406.6°Cat760mmHg
• Flash Point: 195.7°C
• Density: 1.152g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 228.115029749
• Heavy Atom Count: 17
• Complexity: 209

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C(C1=CC=CC=C1)(C2=CC=CC=C2)O)O

Technology Process of 1,1-Diphenyl-1,2-propanediol

There total 22 articles about 1,1-Diphenyl-1,2-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

→ 1,2-bis[4,4-diphenyl-5-methyl-1,3,2-dioxaphospholane-2-yl(2R,5S)]-ethane + 1,1-diphenylpropane-1,2-diol (52183-00-3)

Guidance literature:

Reference yield: 61.0%

1,1-diphenyl-1-propene (778-66-5) → 1,1-diphenylpropane-1,2-diol (52183-00-3)

Guidance literature:

1,1-diphenyl-1-propene; With sodium hydrogencarbonate; 9-(2-mesityl)-10-methylacridinium perchlorate; In acetonitrile; at 20 ℃; for 6h; Irradiation;

With triphenylphosphine; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1039/c7cc06745c

Reference yield: 60.0%

tetraphenylethane-1,2-diol (464-72-2) + acetaldehyde (75-07-0,9002-91-9) → benzophenone (119-61-9) + 1,1-diphenylpropane-1,2-diol (52183-00-3)

Guidance literature:

With titanium(IV) tetrabutoxide; triethylsilyl chloride; In dichloromethane; at 20 ℃;

DOI:10.1002/adsc.201200358

upstream raw materials:

ethyl 2-hydroxypropionate

diethyl ether

2-hydroxypropiophenone

2-Bromopropionic acid

Downstream raw materials:

1,1-diphenylacetone

benzophenone

acetic acid

1,1,4t-triphenyl-but-3-en-2-one

Refernces

• 1、 Yang, Bo,Lu, Zhan. "Visible light-promoted dihydroxylation of styrenes with water and dioxygen". . p. 12634 - 12637. Retrieved 2017/12/02.
• 2、 Murgida, Daniel H.,Aramendia, Pedro F.,Erra-Balsells, Rosa. "Benzophenone-Photosensitized Reactions of Xanthinic Compounds. A Mechanistic Study". . p. 487 - 494. Retrieved 2007/10/03.