Sodium cyanoborohydride

Base Information Edit

Chemical Name:Sodium cyanoborohydride
CAS No.:25895-60-7
Molecular Formula:NaBH3CN
Molecular Weight:62.8423
Hs Code.:2850.00
Mol file:25895-60-7.mol

Synonyms:Sodium cyanoborohydride solution;Sodium cyanobrohydide;sodium; boron(+3) cation; hydrogen(-1) anion; cyanide;Borate(1-), (cyano-kappaC)trihydro-, sodium, (T-4)-;Sodium cyanotrihydroborate;

Suppliers and Price of Sodium cyanoborohydride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Sodium cyanoborohydride
10g
$ 65.00

TCI Chemical
Sodium Cyanoborohydride [Reducing Agent] >95.0%(T)
5g
$ 29.00

TCI Chemical
Sodium Cyanoborohydride [Reducing Agent] >95.0%(T)
250g
$ 597.00

TCI Chemical
Sodium Cyanoborohydride [Reducing Agent] >95.0%(T)
25g
$ 86.00

SynQuest Laboratories
Sodium cyanoborohydride
25 g
$ 105.00

SynQuest Laboratories
Sodium cyanoborohydride
10 g
$ 65.00

Strem Chemicals
Sodium cyanoborohydride, 95%
5g
$ 31.00

Strem Chemicals
Sodium cyanoborohydride, 95%
25g
$ 128.00

Sigma-Aldrich
Sodium cyanoborohydride reagent grade, 95%
1kg
$ 1800.00

Sigma-Aldrich
Sodium cyanoborohydride PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
1kg
$ 1740.00

Total 187 raw suppliers

Chemical Property of Sodium cyanoborohydride Edit

Chemical Property:

Appearance/Colour:white crystalline powder
Melting Point:>242°C (dec.)(lit.)
Boiling Point:307°C
Flash Point:?1°F
PSA：23.79000
Density:1.083 g/mL at 25 °C
LogP:-1.16712
Storage Temp.:Store under Argon
Sensitive.:Moisture Sensitive
Solubility.:H2O: may be clear to slightly hazy
Water Solubility.:2120 g/L at 29 ºC (dec.)
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:63.0256235
Heavy Atom Count:4
Complexity:34.5

Purity/Quality:

99% ^*data from raw suppliers

Sodium cyanoborohydride ^*data from reagent suppliers

Safty Information:

Pictogram(s): F; T+; N
Hazard Codes:T+,N,T,F
Statements: 26/27/28-32-34-50/53-16-15-11-51/53-36-23/24/25-19-14-40-36/37/38
Safety Statements: 26-28-36/37/39-45-60-61-8-50A-43-28A-1-16-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:[BH3-]C#N.[Na+]
Description Sodium cyanoborohydride (NaBH3CN) is a selective reducing agent used for a variety of chemical reductions, including aldehyde, ketones, acetals, epoxides, oximes, enamines, reductive aminations of aldehydes and ketones, and reductive alkylations of amines and hydrazines. The utility of sodium cyanoborohydride as a reducing agent is greatly enhanced by its stability under acid conditions, and its solubility in aprotic solvents. Sodium cyanoborohydride is a milder and more selective reducing agent than sodium borohydride. Sodium cyanoborohydride is a weaker and more-selective reducing agent than sodium borohydride because of the electron-withdrawing effect of the cyano group. It has the further advantage that it is stable in acid to pH = 3 and can be employed to effect reductions in the presence of functional groups that are sensitive to the more-basic conditions of reduction with sodium borohydride. Aldehydes and ketones are unaffected by sodium cyanoborohydride in neutral solution, but they are readily reduced to the corresponding alcohol at pH=3-4 by way of the protonated carbonyl group. By previous exchange of the hydrogens of the borohydride for deuterium or tritium, by reaction with D2O or tritiated water, an efficient and economical route is available for deuteride or tritiide reduction of aldehydes and ketones.
Uses Sodium Cyanoborohydride is a commonly used as a reagent in the reductive amination of aldehydes and ketones and in the reductive alkylation of amines. It is also used in the synthesis of a novel phenolate-bridged dilanthanum(III) complex of interest as a model for metalloproteins as well as for its importance in basic and applied chemistry.

Technology Process of Sodium cyanoborohydride

There total 5 articles about Sodium cyanoborohydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%