Studies on N-Deprotection of ψ(CH2NH)Pseudodipeptide Methyl Esters. Cyclization to 2-Ketopiperazines

DOI: 10.1039/P19910003117

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 3117 - 3120 (1991)

Update date:2022-09-26

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Authors:

Bravo, Ana

Gomez-Monterrey, Isabel

Gonzalez-Muniz, Rosario

Garcia-Lopez, M. Teresa

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Article abstract of DOI:10.1039/P19910003117

N-Deprotection of Z- and Boc-aminomethylene pseudodipeptide methyl esters yielded not only the expected linear deprotected compounds but also the 2-ketopiperazine cyclic analogues.The extent of lactamization was found to be dependent on the nature of the

Full text of DOI:10.1039/P19910003117

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