N-[2-(1-piperazinyl)ethyl]ethylenediamine

Base Information

• Chemical Name: N-[2-(1-piperazinyl)ethyl]ethylenediamine
• CAS No.: 24028-46-4
• Molecular Formula: C8H20 N4
• Molecular Weight: 172.274
• Hs Code.: 2933599090
• European Community (EC) Number: 245-992-8
• DSSTox Substance ID: DTXSID40178772
• Nikkaji Number: J242.721D
• Wikidata: Q83049249
• Mol file: 24028-46-4.mol

Synonyms:24028-46-4;N-[2-(1-piperazinyl)ethyl]ethylenediamine;N-(2-(1-Piperazinyl)ethyl)ethylenediamine;N'-(2-piperazin-1-ylethyl)ethane-1,2-diamine;1,2-Ethanediamine, N-[2-(1-piperazinyl)ethyl]-;N1-(2-(Piperazin-1-yl)ethyl)ethane-1,2-diamine;EINECS 245-992-8;PIPERAZINYLETHYLETHYLENEDIAMINE;N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine;1,2-Ethanediamine, N-(2-(1-piperazinyl)ethyl)-;(2-AMINOETHYL)[2-(PIPERAZIN-1-YL)ETHYL]AMINE;SCHEMBL302850;DTXSID40178772;ZAA02846;N-(2-Piperazinoethyl)-1,2-ethanediamine;N-(2-piperazin-1-yl-ethyl)ethylenediamine;N-[(2-Aminoethyl)2-aminoethyl]piperazine;FT-0700914;EN300-7818384;N-[2-(piperazin-1-yl)ethyl]ethane-1,2-diamine;A901764;1,2-ethanediamine, N1-[2-(1-piperazinyl)ethyl]-;N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine Hydrochloride

Chemical Property of N-[2-(1-piperazinyl)ethyl]ethylenediamine

Chemical Property:

• Vapor Pressure: 0.00183mmHg at 25°C
• Boiling Point: 292.5°C at 760 mmHg
• PKA: 10.04±0.19(Predicted)
• Flash Point: 130.7°C
• PSA: 53.32000
• Density: 0.975g/cm³
• LogP: -0.20220
• XLogP3: -1.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 172.16879665
• Heavy Atom Count: 12
• Complexity: 101

Purity/Quality:

97% ^*data from raw suppliers

N-[2-(1-piperazinyl)ethyl]ethylenediamine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CN(CCN1)CCNCCN
• Uses: N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine is an impurity of Diethylenetriamine (D444255); a compound that is used in biological studies for polyamines inhibition to carbonic anhydrases by anchoring to the zinc-coordinated water molecule.

Technology Process of N-[2-(1-piperazinyl)ethyl]ethylenediamine

There total 10 articles about N-[2-(1-piperazinyl)ethyl]ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyleneimine (151-56-4,9002-98-6) + aminoethylpiperazine (140-31-8) → 1,4-bis(2-aminoethyl)piperazine (6531-38-0) + 1-<2-(2-aminoethyl)aminoethyl>piperazine (24028-46-4)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃;

Reference yield:

triethylentetramine (112-24-3) → piperazine (110-85-0) + aminoethylpiperazine (140-31-8) + 1-<2-(2-aminoethyl)aminoethyl>piperazine (24028-46-4)

Guidance literature:

With hydrogen; nickel on silica/alumina (Sud-Chemie C₄₆-7-03); at 150 ℃; for 6h; under 10379.3 - 32462.1 Torr; Product distribution / selectivity; Autoclave;

Reference yield:

N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine (112-57-2) + triethylentetramine (112-24-3) → piperazine (110-85-0) + aminoethylpiperazine (140-31-8) + 1-<2-(2-aminoethyl)aminoethyl>piperazine (24028-46-4)

Guidance literature:

nickel on silica/alumina (Sud-Chemie C₄₆-7-03); at 155 ℃; for 6h; under 15550.9 - 38512.9 Torr; Product distribution / selectivity; Autoclave;

upstream raw materials:

ethanol

ethylenediamine

ethylene dibromide

1,2-ethanediamine monohydrate

Downstream raw materials:

1-(2-aminoethyl)-4-<(2-aminoethyl)aminoethyl> piperazine

N-(2-aminoethyl)-N'-[2-(1-piperazinyl)ethyl]ethylenediamine