2-Methoxynicotinonitrile

Base Information

Chemical Name:2-Methoxynicotinonitrile
CAS No.:7254-34-4
Molecular Formula:C7H6 N2 O
Molecular Weight:134.1353
Hs Code.:2933399090
European Community (EC) Number:678-932-8
NSC Number:73298
DSSTox Substance ID:DTXSID30291126
Nikkaji Number:J613.831D
Wikidata:Q72517176
Mol file:7254-34-4.mol

Synonyms:2-methoxynicotinonitrile;7254-34-4;3-Cyano-2-methoxypyridine;2-methoxypyridine-3-carbonitrile;2-Methoxy-nicotinonitrile;2-methoxy-3-cyanopyridine;3-PYRIDINECARBONITRILE, 2-METHOXY-;MFCD07363804;NSC73298;NCIOpen2_000556;SCHEMBL564719;DTXSID30291126;terephthalylidenebis(p-nonylaniline);2-Methoxynicotinonitrile, AldrichCPR;BBL012509;NSC 73298;NSC-73298;STK501522;AKOS000198238;PB30871;PS-5495;AC-29630;AM804288;SY039103;CS-0006842;FT-0659646;EN300-30781;A837560;J-512354;Z31131631;2-Methoxynicotinonitrile

Suppliers and Price of 2-Methoxynicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
3-Cyano-2-methoxypyridine
25g
$ 517.00

Alfa Aesar
3-Cyano-2-methoxypyridine, 97+%
5g
$ 440.00

Alfa Aesar
3-Cyano-2-methoxypyridine, 97+%
250mg
$ 39.80

Alfa Aesar
3-Cyano-2-methoxypyridine, 97+%
1g
$ 110.00

Alichem
2-Methoxynicotinonitrile
5g
$ 162.18

Alichem
2-Methoxynicotinonitrile
25g
$ 556.35

Alichem
2-Methoxynicotinonitrile
10g
$ 308.58

Ambeed
2-Methoxynicotinonitrile 95%
10g
$ 162.00

Ambeed
2-Methoxynicotinonitrile 95%
1g
$ 38.00

Ambeed
2-Methoxynicotinonitrile 95%
5g
$ 88.00

Total 43 raw suppliers

Chemical Property of 2-Methoxynicotinonitrile

Chemical Property:

Vapor Pressure:0.0367mmHg at 25°C
Melting Point:58-62 ºC
Boiling Point:241 °C at 760 mmHg
PKA:-0.05±0.10(Predicted)
Flash Point:99.6 °C
PSA：45.91000
Density:1.16 g/cm³
LogP:0.96188
Storage Temp.:Keep Cold
Water Solubility.:Slightly soluble in water.
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:134.048012819
Heavy Atom Count:10
Complexity:149

Purity/Quality:

99%, ^*data from raw suppliers

3-Cyano-2-methoxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC=N1)C#N
Uses 3-Cyano-2-methoxypyridine is used as an organic chemical synthesis intermediate.

Technology Process of 2-Methoxynicotinonitrile

There total 7 articles about 2-Methoxynicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 124-41-4
sodium methylate

: 145325-29-7
2-allylsuphanyl-3-cyanopyridine

: 7254-34-4
2-methoxy-3-cyanopyridine

Guidance literature:: In methanol; Heating;
DOI:10.1002/prac.19923340606

Reference yield: 93.0%

: 67-56-1
methanol

: 6602-54-6
2-chloro-3-pyridinecarbonitrile

: 7254-34-4
2-methoxy-3-cyanopyridine

Guidance literature:: With sodium; for 6h; Reflux;
DOI:10.1016/j.bmc.2011.09.005

Reference yield: 63.0%

: 75-05-8,26809-02-9
acetonitrile

: 163105-90-6
2-methoxypyridin-3-yl-boronic acid

: 7254-34-4
2-methoxy-3-cyanopyridine

Guidance literature:: With N-iodo-succinimide; 1,10-Phenanthroline; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 1,1,1,2,2,2-hexamethyldisilane; oxygen; copper diacetate; diisopropylamine; at 20 - 150 ℃; Schlenk technique;
DOI:10.1002/chem.201501823